Power-optimized drive field coils for human brain magnetic particle imaging

The implementation of human-scale magnetic particle imaging is significantly restricted by the nonlinear growth in power with the size of the field-generating coils. To address this issue, we developed anatomically optimized shapes with a reduced internal volume for the head drive field system using a wide range of anatomical data as a reference. On the base of designed complex bodies, we synthesized windings for two orthogonal coils with the help of the stream functions approach. The resulting coil set was compared to the state-of-the-art solenoid/saddle coil pair and showed a reduction in power consumption by a factor of 1.58 in numerical simulations. We also built a prototype of the designed coils using additive manufacturing and used it to receive the first signals from the nanoparticles.