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27 April 2023
Presentation
Titel
How can digitalization and automation enable large-scale application of CAR-T cell therapies?
Titel Supplements
Presentation held at the Theme Day "The Next Frontiers in ATMP Development", 27-28 April 2023, Langen
Abstract
Many of the challenges in CAR-T cell manufacturing arise from labor intensive manual processes which struggle to account for the biological variability of the patient material. Limited automation options are available and currently the low digitization in the manufacturing process leads to little data available on the process and the final product. To improve data availability digitalization of the manufacturing process is a necessity. Digitization also is a typical enabler for automation, so the AIDPATH project demonstrates a new automation option for CAR-T cell manufacturing, focusing on integrated data acquisition (QC) and processing (artificial intelligence). Within AIDPATH several AI use cases are demonstrated to aid and improve the end-to-end manufacturing process.
Funding(s)
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