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  4. Magnetic particle imaging for assessment of cerebral perfusion and ischemia
 
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2022
  • Zeitschriftenaufsatz

Titel

Magnetic particle imaging for assessment of cerebral perfusion and ischemia

Abstract
Stroke is one of the leading worldwide causes of death and sustained disability. Rapid and accurate assessment of cerebral perfusion is essential to diagnose and successfully treat stroke patients. Magnetic particle imaging (MPI) is a new technology with the potential to overcome some limitations of established imaging modalities. It is an innovative and radiation-free imaging technique with high sensitivity, specificity, and superior temporal resolution. MPI enables imaging and diagnosis of stroke and other neurological pathologies such as hemorrhage, tumors, and inflammatory processes. MPI scanners also offer the potential for targeted therapies of these diseases. Due to lower field requirements, MPI scanners can be designed as resistive magnets and employed as mobile devices for bedside imaging. With these advantages, MPI could accelerate and improve the diagnosis and treatment of neurological disorders. This review provides a basic introduction to MPI, discusses its current use for stroke imaging, and addresses future applications, including the potential for clinical implementation.
Author(s)
Ludewig, Peter
Greaser, Matthias
Forkert, Nils D.
Thieben, Florian
Randez-Garbayo, Javier
Rieckhoff, Johanna
Lessmann, Katrin
Förger, Fynn
Szwargulski, Patryk
Magnus, Tim
Knopp, Tobias
Zeitschrift
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
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DOI
10.1002/wnan.1757
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Language
Englisch
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