Das angeborene Immunsystem in vitro: Die Suche neuer Immuntherapeutika

Pattern recognition receptors (PRRs) are the first defense line of the innate immune system. In the last years PRRs have been studied in different ways resulting in a plethora of new insights. However, until recently it was not possible to investigate individual combinations of PRRs and their specific ligands because of the complex network in immune signaling. An assay developed at Fraunhofer IGB allows to directly analyze the activity of individual human PRR-receptors in a highly specific way.