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  4. Deep Learning-based Detection of Psychiatric Attributes from German Mental Health Records
 
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2022
Journal Article
Title

Deep Learning-based Detection of Psychiatric Attributes from German Mental Health Records

Abstract
Background Health care records provide large amounts of data with real-world and longitudinal aspects, which is advantageous for predictive analyses and improvements in personalized medicine. Text-based records are a main source of information in mental health. Therefore, application of text mining to the electronic health records - especially mental state examination - is a key approach for detection of psychiatric disease phenotypes that relate to treatment outcomes. Methods We focused on the mental state examination (MSE) in the patients' discharge summaries as the key part of the psychiatric records. We prepared a sample of 150 text documents that we manually annotated for psychiatric attributes and symptoms. These documents were further divided into training and test sets. We designed and implemented a system to detect the psychiatric attributes automatically and linked the pathologically assessed attributes to AMDP terminology. This workflow uses a pre-trained neural network model, which is fine-tuned on the training set, and validated on the independent test set. Furthermore, a traditional NLP and rule-based component linked the recognized mentions to AMDP terminology. In a further step, we applied the system on a larger clinical dataset of 510 patients to extract their symptoms. Results The system identified the psychiatric attributes as well as their assessment (normal and pathological) and linked these entities to the AMDP terminology with an F1-score of 86% and 91% on an independent test set, respectively. Conclusion The development of the current text mining system and the results highlight the feasibility of text mining methods applied to MSE in electronic mental health care reports. Our findings pave the way for the secondary use of routine data in the field of mental health, facilitating further clinical data analyses.
Author(s)
Madan, Sumit  
Fraunhofer-Institut für Algorithmen und Wissenschaftliches Rechnen SCAI  
Zimmer, Fabian Julius
Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen
Balabin, Helena
Fraunhofer-Institut für Algorithmen und Wissenschaftliches Rechnen SCAI  
Schaaf, Sebastian
HPC and Scientific Computing, German Center for Neurodegenerative Diseases (DZNE)
Fröhlich, Holger  
Fraunhofer-Institut für Algorithmen und Wissenschaftliches Rechnen SCAI  
Fluck, Juliane
Knowledge Management, ZB MED Information Centre for Life Sciences
Neuner, Irene
Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen
Mathiak, Klaus
Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen
Hofmann-Apitius, Martin  
Fraunhofer-Institut für Algorithmen und Wissenschaftliches Rechnen SCAI  
Sarkheil, Pegah
Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen
Journal
International journal of medical informatics  
Project(s)
i:DSem
i:DSem
i:DSem
HBP SGA2  
Funder
Bundesministerium für Bildung und Forschung BMBF (Deutschland)  
Bundesministerium für Bildung und Forschung BMBF (Deutschland)  
Bundesministerium für Bildung und Forschung BMBF (Deutschland)  
European Commission EC  
Open Access
DOI
10.1016/j.ijmedinf.2022.104724
Language
English
Fraunhofer-Institut für Algorithmen und Wissenschaftliches Rechnen SCAI  
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