• English
  • Deutsch
  • Log In
    Password Login
    Research Outputs
    Fundings & Projects
    Researchers
    Institutes
    Statistics
Repository logo
Fraunhofer-Gesellschaft
  1. Home
  2. Fraunhofer-Gesellschaft
  3. Artikel
  4. Validation of a Web-Based Planning Tool for Percutaneous Cryoablation of Renal Tumors
 
  • Details
  • Full
Options
2020
Journal Article
Title

Validation of a Web-Based Planning Tool for Percutaneous Cryoablation of Renal Tumors

Abstract
Purpose: To validate a simulation environment for virtual planning of percutaneous cryoablation of renal tumors. Materials and Methods: Prospectively collected data from 19 MR-guided procedures were used for validation of the simulation model. Volumetric overlap of the simulated ablation zone volume (S) and the segmented ablation zone volume (S; assessed on 1-month follow-up scan) was quantified. Validation metrics were DICE Similarity Coefficient (DSC; the ratio between twice the overlapping volume of both ablation zones divided by the sum of both ablation zone volumes), target overlap (the ratio between the overlapping volume of both ablation zones to the volume of S; low ratio means S is underestimated), and positive predictive value (the ratio between the overlapping volume of both ablation zones to the volume of S; low ratio means S is overestimated). Values were between 0 (no alignment) and 1 (perfect alignment), a value > 0.7 is considered good. Results: Mean volumes of S and S were 14.8 cm3 (± 9.9) and 26.7 cm3 (± 15.0), respectively. Mean DSC value was 0.63 (± 0.2), and > 0.7 in 9 cases (47%). Mean target overlap and positive predictive value were 0.88 (± 0.11) and 0.53 (± 0.24), respectively. In 17 cases (89%), target overlap was > 0.7; positive predictive value was > 0.7 in 4 cases (21%) and < 0.6 in 13 cases (68%). This indicates S is overestimated in the majority of cases. Conclusion: The validation results showed a tendency of the simulation model to overestimate the ablation effect. Model adjustments are necessary to make it suitable for clinical use.
Author(s)
Oostenbrugge, T.J. van
Heidkamp, J.
Moche, M.
Weir, P.
Mariappan, P.
Flanigan, R.
Pollari, M.
Payne, S.
Kolesnik, M.
Jenniskens, S.F.M.
Fütterer, J.J.
Journal
CardioVascular and interventional radiology  
Project(s)
Go-Smart  
Funder
European Commission EC  
Open Access
DOI
10.1007/s00270-020-02634-y
Additional full text version
Landing Page
Language
English
Fraunhofer-Institut für Angewandte Informationstechnik FIT  
  • Cookie settings
  • Imprint
  • Privacy policy
  • Api
  • Contact
© 2024