Now showing 1 - 2 of 2
  • Publication
    Structure protects function - An enabler for the functionalization of component surfaces by biohybrid coatings
    ( 2022) ;
    Schwaneberg, Ulrich
    ;
    Apelt, Sebastian
    ;
    Jakob, Felix
    ;
    Rodríguez Emmenegger, César
    ;
    Beckers, Alexander
    ;
    Yayci, Abdulkadir
    ;
    Nöth, Maximilian
    ;
    Garay-Sarmiento, Manuela
    ;
    Barth, Sebastian
    The biological transformation is a growing part of current research in manufacturing and enables new possibilities in the development of innovative products. Modular functional assemblies based on biological building blocks potentially enable efficient and economical functionalization of component surfaces. Surface functionalization covers a range of industries and applications with high economic and technological potential and societal relevance. In dentistry, inflammation of the gums near the implant (periimplant infection) is one of the most common complications after implant implantation. The infections are mainly due to bacterial contamination or bacterial colonization at the implant. Biohybrid coatings based on modular functional assemblies represent an innovative solution for surface functionalization to prevent these periimplant infections. However, in addition to the advantages of modular functional assemblies, there are various challenges for the establishment of functional assemblies in series production. These pose new requirements for the manufacturing technology. The aim of interdisciplinary collaboration between biotechnology, soft matter nanotechnology, polymer chemistry, and production engineering is to provide implant surfaces (using titanium dental implants as an example) with an innovative biohybrid coating in combination with microstructuring. The coating prevents the bacterial colonization of the implant while the microstructure increases the robustness and longevity of the coating. The challenges in manufacturing these microstructures of surfaces, the generation of biohybrid coatings as well as an outlook on the innovative use of functionalized surfaces are described in this paper.
  • Publication
    Agile ramp-up production as an advantage of highly iterative product development
    ( 2021) ;
    Apelt, Sebastian
    ;
    Beckers, Alexander
    ;
    Barth, Sebastian
    Current ramp-up productions at manufacturing companies are characterized by a high quantity of unpredicted development efforts. These unpredicted development efforts result in not achieved ramp-up targets such as time-to-market or time-to-volume and in exceeded ramp-up budgets. The highly iterative product development offers the potential to reduce unpredicted development efforts due to the agile approach and the manufacturing of a high quantity of physical prototypes. In the following, agile ramp-up production as the combination of highly iterative product development and ramp-up production is presented as a potential solution approach to optimize and stabilize current ramp-up productions by reducing unpredicted development efforts.