Now showing 1 - 2 of 2
  • Publication
    Workflows for intelligent monitoring using proxy services
    ( 2009) ; ;
    Sfakianakis, S.
    ;
    Sengstag, T.
    Grid technologies have proven to be very successful in the area of eScience, and in particular in healthcare applications. But while the applicability of workflow enacting tools for biomedical research has long since been proven, the practical adoption into regular clinical research has some additional challenges in grid context. In this paper, we investigate the case of data monitoring, and how to seamlessly implement the step between a one-time proof-of-concept workflow and high-performance on-line monitoring of data streams, as exemplified by the case of long-running clinical trials. We will present an approach based on proxy services that allows executing single-run workflows repeatedly with little overhead.
  • Publication
    Building a system for advancing clinico-genomic trials on cancer
    ( 2009)
    Sfakianakis, S.
    ;
    Graf, N.
    ;
    Hoppe, A.
    ;
    ; ;
    Koumakis, L.
    The analysis of clinico-genomic data poses complex computa- tional problems. In the project ACGT, a grid-based software system to sup- port clinicians and bio-statisticians in their daily work is being developed. Starting with a detailed user requirements analysis, and with the continu- ous integration of usability analysis in the development process, the project strives to develop an architecture that will substantially improve the way clinico-genomic trials are conducted today. In this paper, results of the ini- tial requirements analysis and approaches to address these requirements are presented. We also discuss the importance of appropriate metadata to tailor the system to the needs of the users.