Schilling, BastianBastianSchillingBeyersdorf, NiklasNiklasBeyersdorfKerkau, ThomasThomasKerkauGroeber-Becker, Florian KaiFlorian KaiGroeber-Becker2024-09-262024-09-262024-06-12https://publica.fraunhofer.de/handle/publica/475728The present invention relates to solid microbeads having an anti-CD28 monoclonal antibody immobilized thereto for use in the local treatment of malignant melanoma, wherein the anti-CD28 monoclonal antibody binds to an epitope on CD28 outside the C"D loop. The present invention further relates to methods for the local treatment of malignant melanoma comprising the administration of said microbeads.enpatentEP4382131 A1EP20220212011