Fischer, RainerRainerFischerReimann, AndreasAndreasReimannMaskus, Dominika JacquelineDominika JacquelineMaskusFendel, RolfRolfFendelKlockenbring, TorstenTorstenKlockenbring2022-03-082022-03-082016https://publica.fraunhofer.de/handle/publica/311024The technology provided herein relates to novel human antibodies against Plasmodium parasites, in particular against the malaria parasite Plasmodium falciparum. The present disclosure pertains to antibodies against apical membrane antigen 1 (AMA-1). These antibodies have high affinity e.g. to Plasmodium falciparum schizonts and merozoites, inhibit the reinvasion of merozoites into erythrocytes and thereby neutralize parasitic multiplication.en540patent3081575