Tröger, V.V.TrögerScherber, A.A.ScherberMoos, D.D.MoosHowitz, S.S.HowitzBohatzsch, T.T.BohatzschLehes, M.M.LehesTulp, I.I.TulpKuhlmeier, D.D.Kuhlmeier2022-03-132022-03-132016https://publica.fraunhofer.de/handle/publica/397134Chlamydiae are intracellular bacterial pathogens having the ability to cause persistent, often subclinical and mainly sexually transmitted infection (STI). Here, we present a microfluidic device for early diagnosis of STIs. The microfluidic set-up integrates an isothermal nucleic acid amplification driven by internal chemical heating and the detection of the specific amplification product on a lateral flow-based strip. This simple and disposable test platform for the screening of pathogenic Chlamydia trachomatis is a promising tool in home-care diagnosis.enRapid on-chip detection of Chlamydia trachomatis for home-care using loop-mediated isothermal amplificationconference paper