An efficient synthesis of R3Si/CH2/n - substituted acetylacetone derivatives

Urbaniak, W.W.UrbaniakSchubert, U.U.Schubert2022-03-032022-03-031991https://publica.fraunhofer.de/handle/publica/17985310.1002/jlac.1991199101209An efficient synthesis of R3Si(CH2)3CHÄC(O)MeÜ2 3(RMe, OR') is described. The reaction of R3Si(CH2)3Cl 2 with the sodium or potassium salt of acetyacetonate (1) and 0.8-2 equivalents of NaI or KI in DMF, DMSO or NMP as a solvent gives the C- and O-alkylation products R3Si(CH2)3CHÄC(O)MeÜ2 3 and R3Si(CH2)3OC(Me)=CH-C(O)Me 4 in a 3:1 ratio an a 60-70 percent total yield. For R3SiCH2CHÄC(O)MeÜ2 selectivity and yields are lower.enacetylacetonate derivativealkoxy-silaneAnorganiksilane666547An efficient synthesis of R3Si/CH2/n - substituted acetylacetone derivativesjournal article