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July 31, 2025
Paper (Preprint, Research Paper, Review Paper, White Paper, etc.)
Title

Laboratory 4.0 – Next Generation Production in Life Sciences

Title Supplement
Trend report
Abstract
The trend report "Laboratory 4.0 – Next Generation Production in Life Sciences" outlines the vision and implementation of modern, digitized, and automated laboratory environments in the life sciences. The focus is on transforming traditional labs into fully networked, flexible production systems based on Industry 4.0 principles. Enabling technologies such as artificial intelligence, high-speed microscopy, optical coherence tomography, and microfluidic systems are identified as key drivers for increased efficiency, error reduction, and sustainability. The report discusses various levels of automation, particularly in stem cell and tissue production, and presents use cases such as the "StemCellFactory" and "JointPromise". Challenges include system interoperability, regulatory requirements, and the tension between sustainability and compliance. Published by Fraunhofer IPT, the report serves as a guide for the future of biotechnological production.
Author(s)
Janning, Kai  
Fraunhofer-Institut für Produktionstechnologie IPT  
Kaußmann, Frederik
Fraunhofer-Institut für Produktionstechnologie IPT  
Krieger, Judith  orcid-logo
Fraunhofer-Institut für Produktionstechnologie IPT  
Mathews, Julius  
Fraunhofer-Institut für Produktionstechnologie IPT  
Nienhaus, Florian  orcid-logo
Fraunhofer-Institut für Produktionstechnologie IPT  
Reibert, Daniel
Fraunhofer-Institut für Produktionstechnologie IPT  
Stehmar, Charlotte
Fraunhofer-Institut für Produktionstechnologie IPT  
Skazik-Voogt, Claudia  
Fraunhofer-Institut für Produktionstechnologie IPT  
File(s)
Download (1.62 MB)
Rights
Use according to copyright law
DOI
10.24406/publica-4158
Language
English
Fraunhofer-Institut für Produktionstechnologie IPT  
Keyword(s)
  • Automation

  • Digitalization

  • Industry 4.0

  • AI

  • Artificial intelligence

  • Cell production

  • ATMP

  • Tissue engineering

  • Stem cells

  • Inline metrology

  • OCT

  • Optical coherence tomography

  • Micro labs

  • Analytics

  • Diagnostics

  • Sustainability

  • Advanced therapy medicinal products

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