Determination of the Weight of Pharmaceutical Capsules with Dual Energy X-ray Transmission

Pharmaceutical products need to be clean, precisely filled and efficient. Nevertheless, the weight of capsule hulls may vary because of production variations. Due to the fact, that mainly the filled capsules are weighed, the content itself may also vary, which could affect the effectiveness and lead to unwanted adverse effects. Dual energy X-ray transmission (DE-XRT) has proved to be a powerful tool in non-destructive testing and can be used to estimate the weight of materials. As a proof of principle, we examined and weighed free for sale dietary supplement vitamin B capsules with varying content in movement in its blister packaging as this use case is more of economic interest for the industry.