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Patent
Title
Gentechnisch modifizierte Bakteriophagen, insbesondere zur Bekaempfung von pathogenen Prokaryonten bzw. ihrer pathologischen Wirkung, sowie deren Verwendung und Herstellung
Other Title
Genetically modified bacteriophage for controlling pathogenic bacteria has an inducible foreign gene coding for a protein which binds to a molecule involved in transcription, translation, excision or metabolic processes of another phage
Abstract
(A1) Die Erfindung betrifft gentechnisch veraenderte Bakteriophagen und deren Verwendung in einem Verfahren, um mit Hilfe einer viralen Superinfektion durch diese gentechnisch veraenderten Bakteriophagen und deren Transkriptions- bzw. Expressionsprodukte die pathogene bzw. toxische Wirkung von Phagen-infizierten prokaryontischen Krankheitserregern zu blockieren.
;
DE 102007003148 A1 UPAB: 20081002 NOVELTY - Genetically modified bacteriophage has an inducible foreign gene coding for a protein which, after introducing the phage into a prokaryotic host, binds to a DNA, RNA or protein molecule involved in transcription, translation, excision or metabolic processes of another phage that is present in the host, either in lysogenic form or in the form of a plasmid. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a genetically modified bacteriophage with an inducible foreign gene coding for a specific RNA which, after introducing the phage into a prokaryotic host, binds to viral or prokaryotic transcripts as an interfering RNA and thus blocks translation of the transcripts. ACTIVITY - Antibacterial. No biological data given. MECHANISM OF ACTION - Bacteriophage infection. USE - The bacteriophage is useful for infecting prokaryotic organisms (claimed), especially for controlling pathogenic bacteria.
Inventor(s)
Nickisch-Rosenegk, M. von
Patent Number
102007002114
Publication Date
2007
Language
German