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  4. Comorbidity profile of patients with concurrent diagnoses of asthma and COPD in Germany
 
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2020
Journal Article
Title

Comorbidity profile of patients with concurrent diagnoses of asthma and COPD in Germany

Abstract
The aim of this study was to estimate the prevalence of concurrent diagnoses of asthma/COPD and examine its full spectrum of comorbid disorders in Germany. We used nationwide outpatient claims data comprising diagnoses of all statutory health insurees (40+ years) in 2017 (N = 40,477,745). The ICD-10 codes J44 (COPD) and J45 (asthma) were used to identify patients. The odds of 1,060 comorbid disorders were examined in a case-control study design. Of all insurees, 4,632,295 (11%) were diagnosed with either asthma or COPD. Of them, 43% had asthma only, 44% COPD only and 13% both diseases. The prevalence of concurrent asthma/COPD was 1.5% with a slightly higher estimate among females than males (1.6% vs. 1.4%) and constant increase by age in both sexes. Comorbid disorders were very common among these patients. 31 disorders were associated with a strong effect size (odds ratio > 10), including other respiratory diseases, but also bacterial (e.g., mycobacteria, including tuberculosis) and fungal infections (e.g., sporotrichosis and aspergillosis). Patients with concurrent asthma/COPD suffer from comorbid disorders involving various body systems, which points to the need of a multidisciplinary care approach. Regular screening for common comorbid disorders may result in better clinical course and prognosis as well as improvement of patients' quality of life.
Author(s)
Akmatov, Manas K.
Central Research Institute of Ambulatory Health Care in Germany, Berlin
Ermakova, Tatiana  
Fraunhofer-Institut für Offene Kommunikationssysteme FOKUS  
Holstiege, Jakob
Central Research Institute of Ambulatory Health Care in Germany, Berlin
Steffen, Annika
Central Research Institute of Ambulatory Health Care in Germany, Berlin
Stillfried, Dominik von
Central Research Institute of Ambulatory Health Care in Germany, Berlin
Bätzing, Jörg
Central Research Institute of Ambulatory Health Care in Germany, Berlin
Journal
Scientific Reports  
Open Access
DOI
10.1038/s41598-020-74966-1
Language
English
Fraunhofer-Institut für Offene Kommunikationssysteme FOKUS  
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