COVID-19 and the endothelium
There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a generalized inflammatory state and complement elements may together contribute to the overall pro-coagulative state described in COVID-19 patients leading to venular as well as to arteriolar occlusions.
Institute of Biotechnology, Molecular Cell Biology, Brandenburg University of Technology3Cottbus-Senftenberg, Germany
Institute of Microbiology & Virology, Brandenburg Medical School Fontane, Senftenberg, Germany,