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  4. Immune cell-supplemented human skin model for studying fungal infections
 
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2017
Book Article
Titel

Immune cell-supplemented human skin model for studying fungal infections

Abstract
Human skin is a niche for various fungal species which either colonize the surface of this tissue as commensals or, primarily under conditions of immunosuppression, invade the skin and cause infection. Here we present a method for generation of a human in vitro skin model supplemented with immune cells of choice. This model represents a complex yet amenable tool to study molecular mechanisms of host-fungi interactions at human skin.
Author(s)
Kühbacher, Andreas
Sohn, Kai
Burger-Kentischer, Anke
Rupp, Steffen
Hauptwerk
Human fungal pathogen identification. Methods and protocols
Thumbnail Image
DOI
10.1007/978-1-4939-6515-1_25
Language
English
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Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB
Tags
  • 3D skin model

  • immune reaction to fungi

  • host-fungi interaction

  • infection model

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