High (1 GHz) repetition rate compact femtosecond laser: A powerful multiphoton tool for nanomedicine and nanobiotechnology

Multiphoton tomography of human skin and nanosurgery of human chromosomes have been performed with a 1 GHz repetition rate laser by the use of the commercially available femtosecond multiphoton laser tomograph DermaInspect as well as a compact galvoscanning microscope. We performed the autofluorescence tomography up to 100 mu m in the depth of human skin. Submicron cutting lines and hole drillings have been conducted on labeled human chromosomes.