Production of multimodal embolisation particles - challenges and possibilities

Particulate embolisation as a minimally invasive method represents a capable treatment strategy in cancer. To enable the full benefits of embolisation therapy, it would be highly advantageous to have particles which are observable in medical imaging systems such as X-ray or MRI. Bartling et al. [1] already described embolisation particles visible in both imaging systems. Thus, procedure monitoring and follow-up control can be improved considerably. To make this benefit available, the production of multimodal particles has to be cost and time efficient. Today, different production processes are used together with their specific assets and drawbacks. Here, we compare different ways to produce multimodal particles and discuss innovative systems which may allow a time saving production.