A new configurable wireless sensor system for biomedical applications with ISO 18000-3 interface in 0.35 µm CMOS

This article presents a new configurable wireless sensor system. The system is used to perform amperometric measurements and send the measurement data to a handheld reader using a wireless transponder interface. The two-chip sensor system was implemented in a 0.35 mm CMOS technology. The system consists of an integrated nano-potentiostat that performs the actual measurements and an ISO 18000-3 compliant frontend that enables wireless telemetric data transmission and powering of the entire sensor system. The system was manufactured in combination with a chronoamperometric glucose sensor which allows the measurement of the glucose content in tear fluid and thus a non-invasive determination of the blood sugar level. For a range of sensor currents from 0.1 mA to 10 mA, the potentiostat achieved an accuracy of better than 5 % with a total power dissipation of less than 600 mW. With the realized antenna geometry a wireless communication distance of more than 7 cm has been achieved.