Workshop report on the evaluation of the updated and expanded carcinogen database to support derivation of threshold of toxicological concern values for DNA reactive carcinogens

Threshold of toxicological concern (TTC)values are frequently used for compounds occurring at low concentrations in feed and food or as impurities in drugs. This workshop report addressesthe emerging alternatives for deriving TTC values for DNA reactive carcinogens and evaluating the acceptability of the Cramer Class TTC values to be adequately protective for non-DNA reactive carcinogens