A novel multiscale integration approach for vessel enhancement

A novel multiscale integration method to be used for vessel enhancement, called Weighted Additive Response, is presented. It overcomes limitations of the widely used maximum response approach in terms of separation of nearby vessels and robustness to noise. Furthermore, its usefulness as a preprocessing step for a subsequent segmentation is shown. The practicability of the proposed method is quantitatively and qualitatively evaluated with public available artificial and clinical datasets.