Differential expression of myogenic determination genes in musle cells - possible autoactivation by the Myf gene products

The development of muscle cells involves the action of myogenic determination factors. In this report, we show that human skeletal muscle tissue contains, beside the previously described Myf-5, two additional factors Myf-3 and Myf-4 which represent the human homologues of the prodent roteins MyoD1 and myogenin.