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  4. Leveraging 3D convolutional neural network and 3D visible-near-infrared multimodal imaging for enhanced contactless oximetry
 
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2024
Journal Article
Title

Leveraging 3D convolutional neural network and 3D visible-near-infrared multimodal imaging for enhanced contactless oximetry

Abstract
Significance:
Monitoring oxygen saturation (SpO2) is important in healthcare, especially for diagnosing and managing pulmonary diseases. Non-contact approaches broaden the potential applications of SpO2 measurement by better hygiene, comfort, and capability for long-term monitoring. However, existing studies often encounter challenges such as lower signal-to-noise ratios and stringent environmental conditions.

Aim:
We aim to develop and validate a contactless SpO2 measurement approach using 3D convolutional neural networks (3D CNN) and 3D visible-near-infrared (VIS-NIR) multimodal imaging, to offer a convenient, accurate, and robust alternative for SpO2 monitoring.

Approach:
We propose an approach that utilizes a 3D VIS-NIR multimodal camera system to capture facial videos, in which SpO2 is estimated through 3D CNN by simultaneously extracting spatial and temporal features. Our approach includes registration of multimodal images, tracking of the 3D region of interest, spatial and temporal preprocessing, and 3D CNN-based feature extraction and SpO2 regression.

Results:
In a breath-holding experiment involving 23 healthy participants, we obtained multimodal video data with reference SpO2 values ranging from 80% to 99% measured by pulse oximeter on the fingertip. The approach achieved a mean absolute error (MAE) of 2.31% and a Pearson correlation coefficient of 0.64 in the experiment, demonstrating good agreement with traditional pulse oximetry. The discrepancy of estimated SpO2 values was within 3% of the reference SpO2 for ∼80% of all 1-s time points. Besides, in clinical trials involving patients with sleep apnea syndrome, our approach demonstrated robust performance, with an MAE of less than 2% in SpO2 estimations compared to gold-standard polysomnography.

Conclusions:
The proposed approach offers a promising alternative for non-contact oxygen saturation measurement with good sensitivity to desaturation, showing potential for applications in clinical settings.
Author(s)
Liao, Wang
Technische Universität Ilmenau
Zhang, Chen
Technische Universität Ilmenau
Alic, Belmin
Universität Duisburg-Essen
Wildenauer, Alina
Ruhrlandklinik
Dietz-Terjung, Sarah
Ruhrlandklinik
Sucre, Jose Guillermo Ortiz
Ruhrlandklinik
Sutharsan, Sivagurunathan
Ruhrlandklinik
Schoebel, Christoph
Ruhrlandklinik
Seidl, Karsten
Universität Duisburg-Essen
Notni, Gunther  
Fraunhofer-Institut für Angewandte Optik und Feinmechanik IOF  
Journal
Journal of biomedical optics  
Funder
Deutsche Forschungsgemeinschaft  
Open Access
DOI
10.1117/1.JBO.29.S3.S33309
Additional link
Full text
Language
English
Fraunhofer-Institut für Angewandte Optik und Feinmechanik IOF  
Keyword(s)
  • contactless oximetry

  • deep learning

  • multimodal imaging

  • oxygen saturation

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