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  4. Therapy resistance beyond cellular dormancy
 
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2019
Journal Article
Title

Therapy resistance beyond cellular dormancy

Abstract
It is commonly accepted that disseminated tumour cells survive cytotoxic chemotherapy because they are not proliferating. A new study now finds that, in contrast to this long-standing concept, both dormant and proliferative cancer cells can be protected from chemotherapy when they reside at the perivascular niche.
Author(s)
Werner-Klein, M.
Klein, C.A.
Journal
Nature cell biology  
DOI
10.1038/s41556-019-0276-7
Language
English
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin ITEM  
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