Therapeutical immunization of EAV-infected horses by DNA-Vaccination
Equine arteritis virus EAV in the causative agent of the equine viral ateritis. The persistant infection og stallins is the main infection sources for mares, as the infected stallions generally remain asymptomatic while transmitting infections to mares during breeding. These mares inseminated with virus-contaminated semen can have an acute infection, shed large amounts of virus in respiratory secretions and urine, leading to lateral spread of the virus to other susceptible horses. Acute infection of later stages of gestation can lead to abortion. An effective therapeutical vaccination of these horses is highly desirable.