Multicompartment micelles: Has the long-standing dream become a reality?

Multicompartment micelles are complex nanosized systems that possess a hydrosoluble shell and a hydrophobic core, which is characterized by segregated incompatible sub-domains. With roots starting about ten years ago, the field of multicompartment micelles has evolved slowly, until recently when significant achievements have been made. The present article reviews strategies for building such micellar assemblies as well as morphological studies, highlights the future challenges, and discusses possible applications, which exploit the coexistence of differentiated nano-domains.