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2002
Book
Title
Diethylene glycol dimethyl ether
Abstract
Diglyme (CAS No. 111-96-6) is a colourless liquid with a slight, pleasant odour. It is miscible with water and a number of common organic solvents. In the presence of oxidation agents, peroxide may form. Due to its dipolar aprotic properties, diglyme is used mainly as a solvent (semiconductor industry, chemical synthesis, lacquers), as an inert reaction medium in chemical synthesis, and as a separating agent in distillations. Diglyme liquid or vapour is readily absorbed by any route of exposure, metabolized, and excreted mainly in the urine. The main metabolite is 2-methoxyethoxy-acetic acid. 2-Methoxyacetic acid is a minor metabolite; in rats, it amounts to about 5-15% in the urine.