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  4. Corrigendum: Anti-Mesothelin CAR-NK cells as a novel targeted therapy against cervical cancer (Frontiers in Immunology, (2024), 15, (1485461), 10.3389/fimmu.2024.1485461)
 
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2025
Erratum
Title

Corrigendum: Anti-Mesothelin CAR-NK cells as a novel targeted therapy against cervical cancer (Frontiers in Immunology, (2024), 15, (1485461), 10.3389/fimmu.2024.1485461)

Abstract
In the published article, there was an error in Supplementary Figure 8. The graphical data shown in Supplementary Figure 8 was inadvertently duplicated, so that the same data is displayed twice in the figure. This error was present only in the submitted PDF version of the Supplementary Material, while the individually submitted figure files were correct. It appears that an intended edit was not properly incorporated into the final compiled PDF that was uploaded during submission, leading to this unintended duplication. The correct Supplementary Figure 8 appears below. “Supplementary Figure 8 Comparison of 2<sup>nd</sup> and 3<sup>rd</sup> generation CARs. Live cell imaging-based cytotoxicity assays of anti-Mesothelin CAR-NK-92 cells against mCherry<sup>+</sup> SiHa cells. CAR-NK-92 cells were co-cultured with mCherry<sup>+</sup> SiHa cells for 72 hours in a 96-well plate at 1:1 (A) and 1:16 (B) effector to target (E:T) ratios. The anti-tumor activity of the different generations of anti-Mesothelin CAR-NK-92 cells was determined by monitoring the changes in the red-surface area over 72 hours. Data are displayed as mean ± SD, n=3-4, conducted in technical triplicates. Statistical analysis was performed using two-way ANOVA for comparison of 28- BBζ: 3<sup>rd</sup> generation anti-Mesothelin CAR-NK-92 cells (CD28-41BB-CD3ζ) to BBζ: 2<sup>nd</sup> generation (41BB-CD3ζ) and 28ζ: 2<sup>nd</sup> generation (CD28-CD3ζ) anti-Mesothelin CAR-NK-92 cells at 24, 48 and 72 hours. Non-significant differences are indicated as ns.” The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The supplementary material has been updated within the original article.
Author(s)
Kutle, Ivana
Hannover Medical School
Polten, Robert
Hannover Medical School
Stalp, Jan Lennart
Hannover Medical School
Hachenberg, Jens
Hannover Medical School
Todzey, Felix
Hannover Medical School
Hass, Ralf
Hannover Medical School
Zimmermann, Katharina
Hannover Medical School
von der Ohe, Juliane Von Der
Hannover Medical School
von Kaisenberg, Constantin Sylvius
Hannover Medical School
Neubert, Lavinia
Hannover Medical School
Kamp, Jan Christopher
German Center for Lung Research (DZL)
Schaudien, Dirk  
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin ITEM  
Seyda, Ann Kathrin
Hannover Medical School
Hillemanns, Peter A.
Hannover Medical School
Klapdor, Rüdiger
Hannover Medical School
Morgan, Michael Alexander
Hannover Medical School
Schambach, Axel
Hannover Medical School
Journal
Frontiers in Immunology
Open Access
DOI
10.3389/fimmu.2025.1571555
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Fraunhofer-Institut für Toxikologie und Experimentelle Medizin ITEM  
Keyword(s)
  • CAR-NK cells

  • CAR-T cells

  • cervical cancer

  • chemotherapy

  • chimeric antigen receptor (CAR)

  • immunotherapy

  • Mesothelin

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