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  4. Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments
 
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2016
Journal Article
Title

Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments

Abstract
Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the 32P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in "Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice"
Author(s)
Lipka, Jens
CPC, Helmholtz Zentrum München
Semmler-Behnke, Manuela
CPC, Helmholtz Zentrum München
Wenk, Alexander
CPC, Helmholtz Zentrum München
Burkhardt, Jana  
Fraunhofer-Institut für Zelltherapie und Immunologie IZI  
Aigner, Achim
Universität München
Kreyling, Wolfgang
CPC, Helmholtz Zentrum München
Journal
Data in Brief  
Open Access
DOI
10.1016/j.dib.2016.03.092
Additional link
Full text
Language
English
Fraunhofer-Institut für Zelltherapie und Immunologie IZI  
Keyword(s)
  • biokinetic data

  • lung

  • PEI

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