A silicon based microsystem for continuous in vivo glucose monitoring using a new reversible measuring principle

In this paper the concept of an integrated silicon based radioactive sensor microsystem is presented. The sensor is designed for long term measurement of blood glucose concentration of diabetic patients. The sensor itself is implanted. It is controlled and read out by a small external part which contains mergy source, the signal processing circuit and a display unit. The sensor itself is a detector for electron radiation and it is able to measure the ß-activity of 14C labeled lectin molecules. The amount of the lectin molecules in the two measuring chambers changes in one proportional chamber and reversible with changing glucose concentration.