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  4. Identification of Disparities in Personalized Cancer Care - A Joint Approach of the German WERA Consortium
 
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2022
Journal Article
Title

Identification of Disparities in Personalized Cancer Care - A Joint Approach of the German WERA Consortium

Abstract
(1) Background: molecular tumor boards (MTBs) are crucial instruments for discussing and allocating targeted therapies to suitable cancer patients based on genetic findings. Currently, limited evidence is available regarding the regional impact and the outreach component of MTBs; (2) Methods: we analyzed MTB patient data from four neighboring Bavarian tertiary care oncology centers in Würzburg, Erlangen, Regensburg, and Augsburg, together constituting the WERA Alliance. Absolute patient numbers and regional distribution across the WERA-wide catchment area were weighted with local population densities; (3) Results: the highest MTB patient numbers were found close to the four cancer centers. However, peaks in absolute patient numbers were also detected in more distant and rural areas. Moreover, weighting absolute numbers with local population density allowed for identifying so-called white spots-regions within our catchment that were relatively underrepresented in WERA MTBs; (4) Conclusions: investigating patient data from four neighboring cancer centers, we comprehensively assessed the regional impact of our MTBs. The results confirmed the success of existing collaborative structures with our regional partners. Additionally, our results help identifying potential white spots in providing precision oncology and help establishing a joint WERA-wide outreach strategy.
Author(s)
Lüke, Florian  
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin ITEM  
Haller, Florian
Utpatel, Kirsten
Krebs, Markus
Meidenbauer, Norbert
Scheiter, Alexander
Spoerl, Silvia
Heudobler, Daniel
Sparrer, Daniela
Kaiser, Ulrich
Keil, Felix
Schubart, Christoph
Tögel, Lars
Einhell, Sabine
Dietmaier, Wolfgang
Huss, Ralf
Dintner, Sebastian
Sommer, Sebastian
Jordan, Frank
Goebeler, Maria-Elisabeth
Metz, Michaela
Haake, Diana
Scheytt, Mithun
Elena Gerhard-Hartmann
Maurus, Katja
Brändlein, Stephanie
Rosenwald, Andreas
Hartmann, Arndt
Märkl, Bruno
Einsele, Hermann
Mackensen, Andreas
Herr, Wolfgang
Kunzmann, Volker
Bargou, Ralf
Beckmann, Matthias W.
Pukrop, Tobias  
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin ITEM  
Trepel, Martin
Evert, Matthias
Claus, Rainer
Kerscher, Alexander
Journal
Cancers  
Open Access
DOI
10.3390/cancers14205040
Additional link
Full text
Language
English
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin ITEM  
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