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  4. Tumour spectrum and maintance of the Syrian hamster Han:AURA
 
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1997
Conference Paper
Title

Tumour spectrum and maintance of the Syrian hamster Han:AURA

Abstract
The Syrian Hamster strain Han:AURA from the Central Institute of Laboratory Animal Breeding, Hannover, Germany, was used for two long-term studies. In the first experiment an inhalation carcinogenicity study with special wire mesh caging and housing conditions is described. The second experiment was a transplacental carcinogenicity study under conventional caging and housing conditions. One of the main problems in the inhalation study was wet tail-like symptoms which were treated successfully with a fibre enriched-diet. About 30% females and nearly 50% males developed tumours of the adrenal cortex. Interestingly, neuroendocrine cell tumours in the larynx and trachea were observed in about 4 % of each sex. This tumour type is not present in rats and mice. In addition, a giant-cell glioblastoma was detected for the first time in one of the hamsters.
Author(s)
Dasenbrock, C.
Ernst, H.
Rittinghausen, S.
Mainwork
Harmonization of laboratory animal husbandry  
Conference
FELASA Symposium 1996  
Language
English
ITA  
Keyword(s)
  • rodents

  • syrian hamster

  • Tumors

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