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  4. The Liver Tumor Segmentation Benchmark (LiTS)
 
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2023
Journal Article
Title

The Liver Tumor Segmentation Benchmark (LiTS)

Abstract
In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper-/hypo-dense), created in collaboration with seven hospitals and research institutions. Seventy-five submitted liver and liver tumor segmentation algorithms were trained on a set of 131 computed tomography (CT) volumes and were tested on 70 unseen test images acquired from different patients. We found that not a single algorithm performed best for both liver and liver tumors in the three events. The best liver segmentation algorithm achieved a Dice score of 0.963, whereas, for tumor segmentation, the best algorithms achieved Dices scores of 0.674 (ISBI 2017), 0.702 (MICCAI 2017), and 0.739 (MICCAI 2018). Retrospectively, we performed additional analysis on liver tumor detection and revealed that not all top-performing segmentation algorithms worked well for tumor detection. The best liver tumor detection method achieved a lesion-wise recall of 0.458 (ISBI 2017), 0.515 (MICCAI 2017), and 0.554 (MICCAI 2018), indicating the need for further research. LiTS remains an active benchmark and resource for research, e.g., contributing the liver-related segmentation tasks in http://medicaldecathlon.com/. In addition, both data and online evaluation are accessible via https://competitions.codalab.org/competitions/17094.
Author(s)
Bilic, Patrick
Christ, Patrick Ferdinand
Li, Hongwei Bran
Vorontsov, Eugene
Ben-Cohen, Avi
Kaissis, Georgios A.
Szeskin, Adi
Jacobs, Colin J.
Mamani, Gabriel Efrain Humpire
Chartrand, Gabriel
Lohöfer, Fabian K.
Holch, Julian Walter
Sommer, Wieland Heinrich
Hofmann, Felix Oliver
Hostettler, Alexandre
Lev-Cohain, Naama
Drozdzal, Michal
Amitai, Michal Marianne
Vivanti, Refael
Sosna, Jacob
Ezhov, Ivan
Sekuboyina, Anjany Kumar
Navarro, Fernando
Kofler, Florian
Paetzold, Johannes Christian
Shit, Suprosanna
Hu, Xiaobin
Lipková, Jana
Rempfler, Markus
Piraud, Marie
Kirschke, Jan S.
Wiestler, Benedikt
Zhang, Zhiheng
Hülsemeyer, Christian
Beetz, Marcel
Ettlinger, Florian
Antonelli, Michela
Bae, Woong
Bellver, Míriam
Bi, Lei
Chen, Hao
Chlebus, Grzegorz
Fraunhofer-Institut für Digitale Medizin MEVIS  
Dam, Erik Bjørnager
Dou, Qi
Fu, Chi Wing
Giró-I-Nieto, Xavier
Gruen, Felix
Georgescu, Bogdan
Fraunhofer-Institut für Digitale Medizin MEVIS  
Han, Xu
Heng, Pheng Ann
Hesser, Jürgen W.
Igel, Christian
Isensee, Fabian
Moltz, Jan Hendrik
Fraunhofer-Institut für Digitale Medizin MEVIS  
Jaeger, Paul Ferdinand
Jia, Fucang
Kaluva, Krishna Chaitanya
Khened, Mahendra
Kim, Ildoo
Kim, Jae-hun
Kim, Sungwoong
Kohl, Simon A.A.
Konopczyński, Tomasz
Kori, Avinash
Krishnamurthi, Ganapathy
Li, Fan
Li, Hongchao
Li, Junbo
Li, Xiaomeng
Lowengrub, John S.
Ma, Jun
Maier-Hein, Klaus Hermann
Maninis, Kevis Kokitsi
Merhof, Dorit
Meine, Hans
Fraunhofer-Institut für Digitale Medizin MEVIS  
Pai, Akshay
Perslev, Mathias
Petersen, Jens
Pont-Tuset, Jordi
Qi, Jin
Qi, Xiaojuan
Rippel, Oliver
Roth, Karsten
Sarasúa, Ignacio
Shen, Zengming
Schenk, Andrea
Fraunhofer-Institut für Digitale Medizin MEVIS  
Torres, Jordi
Wachinger, Christian
Wang, Chunliang
Weninger, Leon
Wu, Jianrong
Xu, Daguang
Yang, Xiaoping
Yu, Simon Chun Ho
Yuan, Yading
Yue, Miao
Zhang, Liping
Cardoso, Jorge
Bakas, Spyridon
Braren, Rickmer F.
Journal
Medical image analysis : MedIA  
Open Access
DOI
10.1016/j.media.2022.102680
Additional link
Full text
Language
English
Fraunhofer-Institut für Digitale Medizin MEVIS  
Keyword(s)
  • Benchmark

  • CT

  • Deep learning

  • Liver

  • Liver tumor

  • Segmentation

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