DNA-stabilized metal cluster-based nucleic acid-sensor

The present invention pertains to a DNA-stabilized metal cluster-based nucleic acid-sensor which allows quantitative and qualitative detection of oligo- or polynucleotides by measuring a shift in fluorescence intensity between distinct emission wavelengths triggered by target recognition. The invention further pertains to method for detecting a target polynucleotide with a nucleic acid-sensor according to the present invention.