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Patent
Title
Vorrichtung und Verfahren zur Produktion von Singulett-Sauerstoff
Other Title
Apparatus to generate local singlet oxygen for cancer therapy.
Abstract
Es wird eine Vorrichtung zum Erzeugen von Singulett-Sauerstoff mit einer Lichtquelle (1) und einem transparenten Medium (2) beschrieben. Das transparente Medium (2) weist eine erste und eine zweite Oberflaeche auf, wobei die erste Oberflaeche der Lichtquelle (1) zugewandt ist und auf der zweiten Oberflaeche ein Bereich (3) angeordnet ist, der einen Photosensibilisator enthaelt.
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DE 19835456 C UPAB: 19991201 NOVELTY - Apparatus (I) for the production of singlet oxygen from triplet oxygen, has a light source (1) and a transparent medium (2) with two surfaces. The light (1) can be coupled in the transparent medium through the first surface. The second surface has a zone (3) which contains at least one photosensitizer. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a process (II) where singlet oxygen is produced from triplet oxygen by the use of light which is coupled to a transparent medium (2). The light is conducted within the transparent medium (2) to a surface which has a zone (3) containing at least one photosensitizer in contact with triplet oxygen. The triplet oxygen is subjected to a photo-induced excitation to be converted into singlet oxygen through the photosensitizer. MECHANISM OF ACTION - None given. USE - (I) together with a light conductor, is for the emission of oxygen and/or a gas with an oxygen content and/or a photosensitizer. It is used in cancer therapy. ADVANTAGE - The procedure has reduced side effects on the patient, the singlet oxygen is applied locally to the target areas, and the patient does not have to remain for long periods in a darkened environment for an injected photosensitizer to degrade.
Inventor(s)
Koehl, M.
Brucker, Franz
Lieske, V.
Patent Number
1998-19835456
Publication Date
2003
Language
German