Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2021A 12-point recommendation framework to support advancement of the multidisciplinary care of psoriatic arthritis: A call to action
Gratacós, J.; Behrens, F.; Coates, L.C.; Lubrano, E.; Thaçi, D.; Bundy, C.; Torre-Aboki, J. de la; Luelmo, J.; Voorneveld, H.; Richette, P.
Journal Article
2021Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality
Mitra, A.; Suarez-Sharp, S.; Pepin, X.J.H.; Flanagan, T.; Zhao, Y.; Kotzagiorgis, E.; Parrott, N.; Sharan, S.; Tistaert, C.; Heimbach, T.; Zolnik, B.; Sjögren, E.; Wu, F.; Anand, O.; Kakar, S.; Li, M.; Veerasingham, S.; Kijima, S.; Lima Santos, G.M.; Ning, B.; Raines, K.; Rullo, G.; Mandula, H.; Delvadia, P.; Dressman, J.; Dickinson, P.A.; Babiskin, A.
Journal Article
2021An automated and high-throughput-screening compatible pluripotent stem cell-based test platform for developmental and reproductive toxicity assessment of small molecule compounds
Witt, Gesa; Keminer, Oliver; Leu, Jennifer; Tandon, Rashmi; Meiser, Ina; Willing, Anne; Winschel, Ingo; Abt, Jana-Christin; Brändl, Björn; Sébastien, Isabelle; Friese, Manuel A.; Müller, Franz Josef; Neubauer, Julia C.; Claussen, Carsten; Zimmermann, Heiko; Gribbon, Philip; Pless, Ole
Journal Article
2021Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells
Kornstädt, L.; Pierre, S.; Weigert, A.; Ebersberger, S.; Schäufele, T.J.; Kolbinger, A.; Schmid, T.; Cohnen, J.; Thomas, D.; Ferreirós, N.; Brüne, B.; Ebersberger, I.; Scholich, K.
Journal Article
2021Bioaccumulation assessment of nanomaterials using freshwater invertebrate species
Kuehr, Sebastian; Kosfeld, Verena; Schlechtriem, Christian
Journal Article
2021Bioreactor-based antigen production process using the baculovirus expression vector system
Harnischfeger, J.; Käßer, L.; Zitzmann, J.; Salzig, D.; Czermak, P.
Book Article
2021Biotechnological Production and Sensory Evaluation of ω1-Unsaturated Aldehydes
Hammer, A.K.; Emrich, N.O.; Ott, J.; Birk, F.; Fraatz, M.A.; Ley, J.P.; Geissler, T.; Bornscheuer, U.T.; Zorn, H.
Journal Article
2021The CAD risk locus 9p21 increases the risk of vascular calcification in an iPSC-derived VSMC model
Trillhaase, A.; Schmidt, B.; Märtens, M.; Haferkamp, U.; Erdmann, J.; Aherrahrou, Z.
Journal Article
2021Characterization of the Drosophila suzukii β2-tubulin gene and the utilization of its promoter to monitor sex separation and insemination
Yan, Y.; Schwirz, J.; Schetelig, M.F.
Journal Article
2021Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment
Ntari, L.; Nikolaou, C.; Kranidioti, K.; Papadopoulou, D.; Christodoulou-Vafeiadou, E.; Chouvardas, P.; Meier, F.; Geka, C.; Denis, M.C.; Karagianni, N.; Kollias, G.
Journal Article
2021A combined pH and temperature precipitation step facilitates the purification of tobacco-derived recombinant proteins that are sensitive to extremes of either parameter
Opdensteinen, P.; Lobanov, A.; Buyel, J.F.
Journal Article
2021Comparative analysis of point-of-care, high-throughput and laboratory-developed SARS-CoV-2 nucleic acid amplification tests (NATs)
Kohmer, N.; Rabenau, H.F.; Hoehl, S.; Kortenbusch, M.; Ciesek, S.; Berger, A.
Journal Article
2021Compelling Evidence for the Activity of Antiviral Peptides against SARS-CoV-2
Tonk, M.; Růžek, D.; Vilcinskas, A.
Journal Article
2021Complete Metamorphosis in Manduca sexta Involves Specific Changes in DNA Methylation Patterns
Gegner, J.; Vogel, H.; Billion, A.; Förster, F.; Vilcinskas, A.
Journal Article
2021Cottonseed Press Cake as a Potential Diet for Industrially Farmed Black Soldier Fly Larvae Triggers Adaptations of Their Bacterial and Fungal Gut Microbiota
Tegtmeier, D.; Hurka, S.; Klüber, P.; Brinkrolf, K.; Heise, P.; Vilcinskas, A.
Journal Article
2021Cryopreservation of plant cell cultures - Diverse practices and protocols
Nausch, H.; Buyel, J.F.
Journal Article
2021Current State and Future Expectations of Translational Modeling Strategies to Support Drug Product Development, Manufacturing Changes and Controls: A Workshop Summary Report
Pepin, X.J.H.; Parrott, N.; Dressman, J.; Delvadia, P.; Mitra, A.; Zhang, X.; Babiskin, A.; Kolhatkar, V.; Suarez-Sharp, S.
Journal Article
2021Determination of low environmental free cyanide concentrations in freshwaters
Knopf, Burkhard; Rüdel, Heinz; Hansknecht, Dirk; Klawonn, Thorsten; Kreuzer, Knut
Journal Article
2021Development of an Alternative Test System for Chronic Testing of Lotic Macroinvertebrate Species: A Case Study with the Insecticide Imidacloprid
Brüggemann, Maria; Hund-Rinke, Kerstin; Böhmer, Walter; Schäfers, Christoph
Journal Article
2021Development of Fast and Portable Frequency Magnetic Mixing-Based Serological SARS-CoV-2-Specific Antibody Detection Assay
Pietschmann, J.; Voepel, N.; Voß, L.; Rasche, S.; Schubert, M.; Kleines, M.; Krause, H.-J.; Shaw, T.M.; Spiegel, H.; Schroeper, F.
Journal Article
2021Development of Monoclonal Antibodies against Pea Globulins for Multiplex Assays Targeting Legume Proteins
Lidzba, Norbert; García Arteaga, Verónica; Schiermeyer, Andreas; Havenith, Heide; Muranyi, Isabel; Schillberg, Stefan; Lehmann, Jörg; Ueberham, Elke
Journal Article
2021The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines
Robinson, W.J.; Taylor, A.E.; Lauga-Cami, S.; Weaver, G.W.; Arroo, R.R.J.; Kaiser, M.; Gul, S.; Kuzikov, M.; Ellinger, B.; Singh, K.; Schirmeister, T.; Botana, A.; Eurtivong, C.; Bhambra, A.S.
Journal Article
2021Effect of Ecdysterone on the Hepatic Transcriptome and Lipid Metabolism in Lean and Obese Zucker Rats
Marschall, M.J.M.; Ringseis, R.; Gessner, D.K.; Grundmann, S.M.; Most, E.; Wen, G.; Maheshwari, G.; Zorn, H.; Eder, K.
Journal Article
2021Effects of the Gestagen Levonorgestrel in a Life Cycle Test with Zebrafish (Danio rerio)
Teigeler, M.; Schaudien, D.; Böhmer, W.; Länge, R.; Schäfers, C.
Journal Article
2021Effects of Thermal Stress on the Gut Microbiome of Juvenile Milkfish (Chanos chanos)
Hassenrück, Christiane; Reinwald, Hannes; Kunzmann, Andreas; Tiedemann, Inken; Gärdes, Astrid
Journal Article
2021Elevated Expression of Toxin TisB Protects Persister Cells against Ciprofloxacin but Enhances Susceptibility to Mitomycin C
Edelmann, D.; Leinberger, F.H.; Schmid, N.E.; Oberpaul, M.; Schäberle, T.F.; Berghoff, B.A.
Journal Article
2021Engineering a lipoxygenase from cyclocybe aegerita towards long chain polyunsaturated fatty acids
Karrer, D.; Gand, M.; Rühl, M.
Journal Article
2021Entomobacter blattae gen. nov., sp. nov., a new member of the Acetobacteraceae isolated from the gut of the cockroach Gromphadorhina portentosa
Guzman, J.; Sombolestani, A.S.; Poehlein, A.; Daniel, R.; Cleenwerck, I.; Vandamme, P.; Vilcinskas, A.
Journal Article
2021The European Map Butterfly Araschnia levana as a Model to Study the Molecular Basis and Evolutionary Ecology of Seasonal Polyphenism
Baudach, A.; Vilcinskas, A.
Review
2021Expanding the Biocatalytic Toolbox with a New Type of ene/yne-Reductase from Cyclocybe aegerita
Karrer, D.; Gand, M.; Rühl, M.
Journal Article
2021Exploring unknown per- and polyfluoroalkyl substances in the German environment
Göckener, Bernd; Fliedner, Annette; Rüdel, Heinz; Fettig, Ina; Koschorreck, Jan
Journal Article
2021Exposure to low doses of pesticides induces an immune response and the production of nitric oxide in honeybees
Bartling, M.T.; Thümecke, S.; Russert, J.H.; Vilcinskas, A.; Lee, K.-Z.
Journal Article
2021First time β-farnesene production by the versatile bacterium Cupriavidus necator
Milker, S.; Holtmann, D.
Journal Article
2021Flavonol glycosides from aerial parts of Astragalus thracicus Griseb
Vasilev, H.; Šmejkal, K.; Gronover, C.S.; Choi, Y.H.; Prüfer, D.; Jankovská, D.; Ionkova, I.
Journal Article
2021Genetic Analysis of MPO Variants in Four Psoriasis Subtypes in Patients from Germany
Haskamp, S.; Horowitz, J.S.; Oji, V.; Philipp, S.; Sticherling, M.; Schäkel, K.; Schuhmann, S.; Prinz, J.C.; Burkhardt, H.; Behrens, F.; Böhm, B.; Köhm, M.; Rech, J.; Simon, D.; Schett, G.; Morrison, K.; Gerdes, S.; Assmann, G.; Nimeh, A.; Schuster, V.; Jacobi, A.; Weyergraf, A.; Reis, A.; Uebe, S.; Wilsmann-Theis, D.; Mößner, R.; Hüffmeier, U.
Letter to the Editor
2021Genomic analysis of novel Yarrowia-like yeast symbionts associated with the carrion-feeding burying beetle Nicrophorus vespilloides
Brinkrolf, K.; Shukla, S.P.; Griep, S.; Rupp, O.; Heise, P.; Goesmann, A.; Heckel, D.G.; Vogel, H.; Vilcinskas, A.
Journal Article
2021Gram-scale production of the sesquiterpene α-humulene with Cupriavidus necator
Milker, S.; Sydow, A.; Torres-Monroy, I.; Jach, G.; Faust, F.; Kranz, L.; Tkatschuk, L.; Holtmann, D.
Journal Article
2021Heterologous Expression of Pseudouridimycin and Description of the Corresponding Minimal Biosynthetic Gene Cluster
Böhringer, N.; Patras, M.A.; Schäberle, T.F.
Journal Article
2021Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial
Sulyok, Z.; Fendel, R.; Eder, B.; Lorenz, F.-R.; Kc, N.; Karnahl, M.; Lalremruata, A.; Nguyen, T.T.; Held, J.; Adjadi, F.A.C.; Klockenbring, Torsten; Flügge, J.; Woldearegai, T.G.; Lamsfus Calle, C.; Ibáñez, J.; Rodi, M.; Egger-Adam, D.; Kreidenweiss, A.; Köhler, C.; Esen, M.; Sulyok, M.; Manoj, A.; Richie, T.L.; Sim, B.K.L.; Hoffman, S.L.; Mordmüller, B.; Kremsner, P.G.
Journal Article
2021Hg isotopic composition of one-year-old spruce shoots: Application to long-term Hg atmospheric monitoring in Germany
Yamakawa, A.; Amouroux, D.; Tessier, E.; Bérail, S.; Fettig, I.; Barre, J.P.G.; Koschorreck, J.; Rüdel, H.; Donard, O.F.X.
Journal Article
2021Holobiont nitrogen control and its potential for eutrophication resistance in an obligate photosymbiotic jellyfish
Röthig, T.; Puntin, G.; Wong, J.C.Y.; Burian, A.; McLeod, W.; Baker, D.M.
Journal Article
2021Human Mesenchymal Stromal Cells Are Resistant to SARS-CoV-2 Infection under Steady-State, Inflammatory Conditions and in the Presence of SARS-CoV-2-Infected Cells
Schäfer, R.; Spohn, G.; Bechtel, M.; Bojkova, D.; Baer, P.C.; Kuci, S.; Seifried, E.; Ciesek, S.; Cinatl, J.
Journal Article
2021The immune suppressive microenvironment affects efficacy of radio-immunotherapy in brain metastasis
Niesel, K.; Schulz, M.; Anthes, J.; Alekseeva, T.; Macas, J.; Salamero-Boix, A.; Möckl, A.; Oberwahrenbrock, T.; Lolies, M.; Stein, S.; Plate, K.H.; Reiss, Y.; Rödel, F.; Sevenich, L.
Journal Article
2021The immunomodulatory potential of the arylmethylaminosteroid sc1o
Blum, L.; Ulshöfer, T.; Henke, M.; Krieg, R.; Berneburg, I.; Geisslinger, G.; Becker, K.; Parnham, M.J.; Schiffmann, S.
Journal Article
2021Impact of nicotine pathway downregulation on polyamine biosynthesis and leaf ripening in tobacco
Nölke, G.; Chudobova, I.; Houdelet, M.; Volke, D.; Lusso, M.; Frederick, J.; Kudithipudi, C.; Shen, Y.; Warek, U.; Strickland, J.A.; Xu, D.; Schinkel, H.; Schillberg, S.
Journal Article
2021Improved degradation of azo dyes by lignin peroxidase following mutagenesis at two sites near the catalytic pocket and the application of peroxidase-coated yeast cell walls
Ilić Đurđić, K.; Ostafe, R.; Prodanovic, O.; Đurđević Đelmaš, A.; Popović, N.; Fischer, R.; Schillberg, S.; Prodanovic, R.
Journal Article
2021Improving target assessment in biomedical research: The GOT-IT recommendations
Emmerich, C.H.; Gamboa, L.M.; Hofmann, M.C.J.; Bonin-Andresen, M.; Arbach, O.; Schendel, P.; Gerlach, B.; Hempel, K.; Bespalov, A.; Dirnagl, U.; Parnham, M.J.
Journal Article
2021In vitro characterization of 3-chloro-4-hydroxybenzoic acid building block formation in ambigol biosynthesis
Kresna, I.D.M.; Linares-Otoya, L.; Milzarek, T.; Duell, E.R.; Mir Mohseni, M.; Mettal, U.; König, G.M.; Gulder, T.A.M.; Schäberle, T.F.
Journal Article
2021Influence of a Biotechnologically Produced Oyster Mushroom (Pleurotus sajor-caju) on the Gut Microbiota and Microbial Metabolites in Obese Zucker Rats
Maheshwari, G.; Gessner, D.K.; Neuhaus, K.; Most, E.; Zorn, H.; Eder, K.; Ringseis, R.
Journal Article
2021Ingestion of bivalve droppings by benthic invertebrates may lead to the transfer of nanomaterials in the aquatic food chain
Kuehr, Sebastian; Diehle, Noemi; Kägi, Ralf; Schlechtriem, Christian
Journal Article
2021Interprofessionelle Versorgung von Patienten mit rheumatoider Arthritis aus hausärztlicher Sicht: Ergebnisse einer Querschnittserhebung
Schneider, E.; Petersen, J.J.; Schulz-Rothe, S.; Gerlach, F.M.; Rossmanith, T.; Siebenhofer, A.; Mergenthal, K.
Journal Article
2021Iron-Bound Lipocalin-2 from Tumor-Associated Macrophages Drives Breast Cancer Progression Independent of Ferroportin
Mertens, C.; Schnetz, M.; Rehwald, C.; Grein, S.; Elwakeel, E.; Weigert, A.; Brüne, B.; Jung, M.
Journal Article
2021Isolation and light chain shuffling of a Plasmodium falciparum AMA1-specific human monoclonal antibody with growth inhibitory activity
Seidel-Greven, M.; Addai-Mensah, O.; Spiegel, H.; Chiegoua Dipah, G.N.; Schmitz, S.; Breuer, G.; Frempong, M.; Reimann, A.; Klockenbring, T.; Fischer, R.; Barth, S.; Fendel, R.
Journal Article
2021Isolation of a gene cluster from Armillaria gallica for the synthesis of armillyl orsellinate-type sesquiterpenoids
Engels, B.; Heinig, U.; McElroy, C.; Meusinger, R.; Grothe, T.; Stadler, M.; Jennewein, S.
Journal Article
2021Lipidomic analysis of local inflammation models shows a specific systemic acute phase response to lipopolysaccharides
Hahnefeld, L.; Kornstädt, L.; Kratz, D.; Ferreiros, N.; Geisslinger, G.; Pierre, S.; Scholich, K.
Journal Article
2021Long-term trends of airborne halogenated flame retardants (HFRs) by means of tree leaf and shoot analyses
Dreyer, A.; Neugebauer, F.; Lohmann, N.; Rüdel, H.; Tarricone, K.; Rauert, C.; Koschorreck, J.
Journal Article
2021Machine learning suggests sleep as a core factor in chronic pain
Miettinen, T.; Mäntyselkä, P.; Hagelberg, N.; Mustola, S.; Kalso, E.; Lötsch, J.
Journal Article
2021Microbial Population Dynamics in Model Sewage Treatment Plants and the Fate and Effect of Gold Nanoparticles
Schlich, K.; Diaz, C.; Gomez Pizarro, B.; Knopf, B.; Schlinkert, R.; Wege, F.F.; Jurack, A.; Hund-Rinke, K.
Journal Article
2021Microparticle formulations alter the toxicity of fenofibrate to the zebrafish Danio rerio embryo
Hering, Indra; Eilebrecht, Elke; Parnham, Michael J.; Weiler, Marc; Günday-Türeli, Nazende; Türeli, Akif Emre; Modh, Harshvardhan; Heng, Paul W.S.; Böhmer, Walter; Schäfers, Christoph; Fenske, Martina; Wacker, Matthias G.
Journal Article
2021Microscopic and Transcriptomic Analysis of Pollination Processes in Self-Incompatible Taraxacum koksaghyz
Wollenweber, T.E.; Deenen, N. van; Roelfs, K.-U.; Prüfer, D.; Gronover, C.S.
Journal Article
2021Morphological Analysis Reveals a Compartmentalized Duct in the Venom Apparatus of the Wasp Spider (Argiope bruennichi)
Schmidtberg, H.; Reumont, B.M. von; Lemke, S.; Vilcinskas, A.; Lüddecke, T.
Journal Article
2021Nelfinavir and Its Active Metabolite M8 Are Partial Agonists and Competitive Antagonists of the Human Pregnane X Receptor
Burk, O.; Kronenberger, T.; Keminer, O.; Lee, S.M.L.; Schiergens, T.S.; Schwab, M.; Windshügel, B.
Journal Article
2021On the verge of the market – Plant factories for the automated and standardized production of biopharmaceuticals
Huebbers, J.W.; Buyel, J.F.
Review
2021Optimization of heterologous Darobactin A expression and identification of the minimal biosynthetic gene cluster
Wuisan, Z.G.; Kresna, I.D.M.; Böhringer, N.; Lewis, K.; Schäberle, T.F.
Journal Article
2021Organization of the Structural Protein Region of La Jolla Virus Isolated from the Invasive Pest Insect Drosophila suzukii
Carrau, T.; Lamp, B.; Reuscher, C.M.; Vilcinskas, A.; Lee, K.-Z.
Journal Article
2021Plant molecular farming for the production of valuable proteins - Critical evaluation of achievements and future challenges
Schillberg, S.; Finnern, R.
Review
2021Plant-made immunotoxin building blocks: A roadmap for producing therapeutic antibody-toxin fusions
Knödler, M.; Buyel, J.F.
Journal Article
2021Post-transcriptional deregulation of the tisB/istR-1 toxin–antitoxin system promotes SOS-independent persister formation in Escherichia coli
Edelmann, D.; Oberpaul, M.; Schäberle, T.F.; Berghoff, B.A.
Journal Article
2021Predicting the environmental emissions arising from conventional and nanotechnology-related pharmaceutical drug products
Jung, Fabian; Thurn, Manuela; Krollik, Katharina; Gao, Ge Fiona; Hering, Indra; Eilebrecht, Elke; Emara, Yasmine; Weiler, Marc; Günday-Türeli, Nazende; Türeli, Emre; Parnham, Michael J.; Wacker, Matthias G.
Journal Article
2021Process Design for the Production of Prebiotic Oligosaccharides in an Enzyme Membrane Bioreactor: Interaction between Enzymatic Reaction and Membrane Filtration 
Fan, R.; Burghardt, J.P.; Dresler, J.; Czermak, P.
Journal Article
2021Production of baculovirus and stem cells for baculovirus-mediated gene transfer into human mesenchymal stem cells
Eilts, F.; Harnischfeger, J.; Loewe, D.; Wolff, M.W.; Salzig, D.; Czermak, P.
Book Article
2021Purification of Crude Fructo-Oligosaccharide Preparations Using Probiotic Bacteria for the Selective Fermentation of Monosaccharide Byproducts
Fan, R.; Burghardt, J.P.; Huang, J.; Xiong, T.; Czermak, P.
Journal Article
2021Regulatory bioaccumulation assessment of nanomaterials. Development of new concepts and testing procedures
Kühr, Sebastian
: Schlechtriem, Christian; Schönherr, Holger
Dissertation
2021The role of environmental specimen banks in monitoring environmental contamination
Chaplow, Jacqueline S.; Bond, Alexander L.; Koschorreck, Jan; Rüdel, Heinz; Shore, Richard F.
Book Article
2021Role of Tristetraprolin in the Resolution of Inflammation
Rappl, P.; Brüne, B.; Schmid, T.
Review
2021Scope and limitations of biocatalytic carbonyl reduction with white-rot fungi
Zhuk, T.S.; Skorobohatko, O.S.; Albuquerque, W.; Zorn, H.
Journal Article
2021Selection and characterization of two monoclonal antibodies specific for the Aspergillus flavus major antigenic cell wall protein Aflmp1
Ansari, S.; Mousavi, A.; Safarnejad, M.R.; Farrokhi, N.; Alavi, S.M.; Schillberg, S.; Nölke, G.
Journal Article
2021Sensor platform for rapid detection and quantification of indicator and pathogenic bacteria on food contact surfaces
Badalyan, Grigori
: Lipski, André; Bücking, Mark; Stamminger, Rainer
Dissertation
2021A series of meroterpenoids with rearranged skeletons from an endophytic fungus Penicillium sp. GDGJ-285
Mo, T.-X.; Huang, X.-S.; Zhang, W.-X.; Schäberle, T.F.; Qin, J.-K.; Zhou, D.-X.; Qin, X.-Y.; Xu, Z.-L.; Li, J.; Yang, R.-Y.
Journal Article
2021Serum 4β-hydroxycholesterol increases during fluconazole treatment
Lütjohann, D.; Stellaard, F.; Kerksiek, A.; Lötsch, J.; Oertel, B.G.
Journal Article
2021Simulation of oral absorption from non-bioequivalent dosage forms of the salt of raltegravir, a poorly soluble acidic drug, using a physiologically based biopharmaceutical modeling (PBBM) approach
Komasaka, T.; Dressman, J.
Journal Article
2021Substrate Inhibition of 5β-Δ4-3-Ketosteroid Dehydrogenase in Sphingobium sp. Strain Chol11 Acts as Circuit Breaker During Growth With Toxic Bile Salts
Feller, F.M.; Marke, G.; Drees, S.L.; Wöhlbrand, L.; Rabus, R.; Philipp, B.
Journal Article
2021Sugarcane cystatins: From discovery to biotechnological applications
Tanaka Shibao, Priscila Yumi; Santos-Junior, Celio Dias; Santiago, Adelita Carolina; Mohan, Chakravarthi; Miguel, Mariana Cardoso; Toyama, Danyelle; Sanches Vieira, Marcos Antonio; Narayanan, Subramonian; Figueira, Antonio; Carmona, Adriana K.; Schiermeyer, Andreas; Soares-Costa, Andrea; Henrique-Silva, Flavio
Journal Article
2021Surveillance of SARS-CoV-2 in Frankfurt am Main from October to December 2020 Reveals High Viral Diversity Including Spike Mutation N501Y in B.1.1.70 and B.1.1.7
Widera, M.; Mühlemann, B.; Corman, V.M.; Toptan, T.; Beheim-Schwarzbach, J.; Kohmer, N.; Schneider, J.; Berger, A.; Veith, T.; Pallas, C.; Bleicker, T.; Goetsch, U.; Tesch, J.; Gottschalk, R.; Jones, T.C.; Ciesek, S.; Drosten, C.
Journal Article
2021Tandem mass tag-based proteomics for studying the effects of a biotechnologically produced oyster mushroom against hepatic steatosis in obese Zucker rats
Maheshwari, G.; Wen, G.; Gessner, D.K.; Ringseis, R.; Lochnit, G.; Eder, K.; Zorn, H.; Timm, T.
Journal Article
2021Targeted genome editing of plants and plant cells for biomanufacturing
Buyel, J.F.; Stöger, E.; Bortesi, L.
Journal Article
2021Testing the bioaccumulation potential of manufactured nanomaterials in the freshwater amphipod Hyalella azteca
Kühr, Sebastian; Kaegi, R.; Maletzki, D.; Schlechtriem, C.
Journal Article
2021Therapeutic Targeting of MicroRNAs in the Tumor Microenvironment
Raue, R.; Frank, A.-C.; Syed, S.N.; Brüne, B.
Review
2021Tick defensin γ-core reduces Fusarium graminearum growth and abrogates mycotoxins production with high efficiency
Leannec-Rialland, V.; Cabezas-Cruz, A.; Atanasova, V.; Chereau, S.; Ponts, N.; Tonk, M.; Vilcinskas, A.; Ferrer, N.; Valdes, J.J.; Richard-Forget, F.
Journal Article
2021Tofacitinib as monotherapy following methotrexate withdrawal in patients with psoriatic arthritis previously treated with open-label tofacitinib plus methotrexate
Nash, P.; Mease, P.J.; Fleishaker, D.; Wu, J.; Coates, L.C.; Behrens, F.; Gladman, D.D.; Kivitz, A.J.; Wei, J.C.; Shirinsky, I.; Menon, S.; Romero, A.B.; Fallon, L.; Hsu, M.-A.; Wang, C.; Kanik, K.S.
Journal Article
2021Toxicogenomic differentiation of functional responses to fipronil and imidacloprid in Daphnia magna
Pfaff, Julia; Reinwald, Hannes; Ayobahan, Steve U.; Alvincz, Julia; Göckener, Bernd; Shomroni, Orr; Salinas, Gabriela; Düring, Rolf-Alexander; Schäfers, Christoph; Eilebrecht, Sebastian
Journal Article
2021Toxicogenomic fin(ger)prints for thyroid disruption AOP refinement and biomarker identification in zebrafish embryos
Reinwald, Hannes; König, Azora; Ayobahan, Steve U.; Alvincz, Julia; Sipos, Levente; Göckener, Bernd; Böhle, Gisela; Shomroni, Orr; Hollert, Henner; Salinas, Gabriela; Schäfers, Christoph; Eilebrecht, Elke; Eilebrecht, Sebastian
Journal Article
2021Transcriptome of different fruiting stages in the cultivated mushroom Cyclocybe aegerita suggests a complex regulation of fruiting and reveals enzymes putatively involved in fungal oxylipin biosynthesis
Orban, A.; Weber, A.; Herzog, R.; Hennicke, F.; Rühl, M.
Journal Article
2021Trial of upadacitinib and adalimumab for psoriatic arthritis
McInnes, I.B.; Anderson, J.K.; Magrey, M.; Merola, J.F.; Liu, Y.; Kishimoto, M.; Jeka, S.; PachecoTena, C.; Wang, X.; Chen, L.; Zueger, P.; Liu, J.; Pangan, A.L.; Behrens, F.
Journal Article
2021Tribolium castaneum defensin 1 kills Moraxella catarrhalis in an in vitro infection model but does not harm commensal bacteria
Bertrams, W.; Lindhauer, N.S.; Rieke, M.C.; Paas, A.; Hoffmann, K.; Greene, B.; Visekruna, A.; Vilcinskas, A.; Seidel, K.; Schmeck, B.
Journal Article
2021Typical symptoms of common otorhinolaryngological diseases may mask a SARS-CoV-2 infection
Weiss, R.; Guchlerner, L.; Loth, A.G.; Leinung, M.; Wicker, S.; Kempf, V.A.J.; Berger, A.; Rabenau, H.F.; Ciesek, S.; Stöver, T.; Diensthuber, M.
Journal Article
2021Upstream and downstream processes for viral nanoplexes as vaccines
Lothert, K.; Dekevic, G.; Loewe, D.; Salzig, D.; Czermak, P.; Wolff, M.W.
Book Article
2021Uptake of perfluorinated alkyl acids by crops: Results from a field study
Felizeter, Sebastian; Jürling, Heinrich; Kotthoff, Matthias; Voogt, Pim de; McLachlan, Michael S.
Journal Article
2021Using in silico modelling and FRET-based assays in the discovery of novel FDA-approved drugs as inhibitors of MERS-CoV helicase
Mehyar, N.; Mashhour, A.; Islam, I.; Gul, S.; Adedeji, A.O.; Askar, A.S.; Boudjelal, M.
Journal Article
2021Welche Prozesse sind für das Umweltverhalten von PFAS im Boden verantwortlich?
Weidemann, E.; Kowalczyk, J.; Just, H.; Breuer, J.; Göckener, B.; Lämmer, R.; Stahl, T.; Bücking, M.; Gaßmann, M.
Journal Article
202012/15-Lipoxygenase choreographs the resolution of IgG-mediated skin inflammation
Sezin, T.; Ferreiros, N.; Jennrich, M.; Ochirbold, K.; Seutter, M.; Attah, C.; Mousavi, S.; Zillikens, D.; Geisslinger, G.; Sadik, C.D.
Journal Article
2020A 3D Human Liver Model of Nonalcoholic Steatohepatitis
Duriez, M.; Jacquet, A.; Hoet, L.; Roche, S.; Bock, M.-D.; Rocher, C.; Haussy, G.; Vigé, X.; Bocskei, Z.; Slavnic, T.; Martin, V.; Guillemot, J.-C.; Didier, M.; Kannt, A.; Orsini, C.; Mikol, V.; Le Fèvre, A.-C.
Journal Article
20204-(4-Chlorophenyl)thiazol-2-amines as pioneers of potential neurodegenerative therapeutics with anti-inflammatory properties based on dual DNase I and 5-LO inhibition
Smelcerovic, A.; Zivkovic, A.; Ilic, B.S.; Kolarevic, A.; Hofmann, B.; Steinhilber, D.; Stark, H.
Journal Article
2020ABC transporter DerAB of lactobacillus casei mediates resistance against insect-derived defensins
Revilla-Guarinos, A.; Zhang, Q.; Loderer, C.; Alcántara, C.; Müller, A.; Rahnamaeian, M.; Vilcinskas, A.; Gebhard, S.; Zúñiga, M.; Mascher, T.
Journal Article
2020ACE inhibitors in SSc patients display a risk factor for scleroderma renal crisis - a EUSTAR analysis
Bütikofer, L.; Varisco, P.A.; Distler, O.; Kowal-Bielecka, O.; Allanore, Y.; Riemekasten, G.; Villige, P.M.; Adler, S.; Burkhardt, H. et al.
Journal Article
2020Achilles tendon enthesitis evaluated by MRI assessments in patients with axial spondyloarthritis and psoriatic arthritis: a report of the methodology of the ACHILLES trial
Baraliakos, X.; Sewerin, P.; Miguel, E. de; Pournara, E.; Kleinmond, C.; Wiedon, A.; Behrens, F.
Journal Article
2020Ad hoc laboratory-based surveillance of SARS-CoV-2 by real-time RT-PCR using minipools of RNA prepared from routine respiratory samples
Eis-Hübinger, A.M.; Hönemann, M.; Wenzel, J.J.; Berger, A.; Widera, M.; Schmidt, B.; Aldabbagh, S.; Marx, B.; Streeck, H.; Ciesek, S.; Liebert, U.G.; Huzly, D.; Hengel, H.; Panning, M.
Journal Article
2020Addendum to S3-Guidelines Crohn's disease and ulcerative colitis: Management of Patients with Inflammatory Bowel Disease in the COVID-19 Pandemic - open questions and answers
Stallmach, A.; Sturm, A.; Blumenstein, I.; Helwig, U.; Koletzko, S.; Lynen, P.; Schmidt, C.; Dignass, A.; Kucharzik, T.
Journal Article
2020Addendum zu den S3-Leitlinien Morbus Crohn und Colitis ulcerosa: Betreuung von Patienten mit chronisch entzündlichen Darmerkrankungen in der COVID-19-Pandemie - offene Fragen und Antworten
Stallmach, A.; Sturm, A.; Blumenstein, I.; Helwig, U.; Koletzko, S.; Lynen, P.; Schmidt, C.; Dignaß, A.; Kucharzik, T.
Journal Article
2020ADTRP regulates TFPI expression via transcription factor POU1F1 involved in coronary artery disease
Luo, C.; Pook, E.; Wang, F.; Archacki, S.R.; Tang, B.; Zhang, W.; Hu, J.-S.; Yang, J.; Leineweber, K.; Bechem, M.; Huang, W.; Song, Y.; Cheung, S.-H.; Laux, V.; Ke, T.; Ren, X.; Tu, X.; Chen, Q.; Wang, Q.K.; Xu, C.
Journal Article
2020Agrocybe aegerita Serves as a Gateway for Identifying Sesquiterpene Biosynthetic Enzymes in Higher Fungi
Zhang, C.; Chen, X.; Orban, A.; Shukal, S.; Birk, F.; Too, H.-P.; Rühl, M.
Journal Article
2020Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis
Queck, A.; Fink, A.F.; Sirait-Fischer, E.; Rüschenbaum, S.; Thomas, D.; Snodgrass, R.G.; Geisslinger, G.; Baba, H.A.; Trebicka, J.; Zeuzem, S.; Weigert, A.; Lange, C.M.; Brüne, B.
Journal Article
2020Alternatives to Growth. Climax Economy Modelled on Ecology
Schäfers, Christoph; Bette, Kristina; Herrmann, Florian; Nawroth, Georg
Book Article
2020AMPKβ1 and AMPKβ2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification
Ziegler, N.; Bader, E.; Epanchintsev, A.; Margerie, D.; Kannt, A.; Schmoll, D.
Journal Article
2020Analysis of potential risk factors of caprine coccidiosis
Silva, L.M.R.; Carrau, T.; Vila-Viçosa, M.J.M.; Musella, V.; Rinaldi, L.; Failing, K.; Cortes, H.C.E.; Taubert, A.; Hermosilla, C.
Journal Article
2020Analysis of proximal ALOX5 promoter binding proteins by quantitative proteomics
Schlag, K.; Steinhilber, D.; Karas, M.; Sorg, B.L.
Journal Article
2020Angiotensin II treatment in COVID-19 patients: More risk than benefit? A single-center experience
Heinicke, U.; Adam, E.; Sonntagbauer, M.; Knethen, A. von; Zacharowski, K.; Neb, H.
Journal Article
2020Anthelminthic Activity of Assassin Bug Venom against the Blood Fluke Schistosoma mansoni
Tonk, M.; Vilcinskas, A.; Grevelding, C.G.; Haeberlein, S.
Journal Article
2020An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products
Jiménez, M. de los Reyes; Lechner, A.; Alessandrini, F.; Bohnacker, S.; Schindela, S.; Trompette, A.; Haimerl, P.; Thomas, D.; Henkel, F.; Mourão, A.; Geerlof, A.; Costa, C.P. da; Chaker, A.M.; Brüne, B.; Nüsing, R.; Jakobsson, P.-J.; Nockher, W.A.; Feige, M.J.; Haslbeck, M.; Ohnmacht, C.; Marsland, B.J.; Voehringer, D.; Harris, N.L.; Schmidt-Weber, C.B.; Esser-von Bieren, J.
Journal Article
2020Antibacterial scalarane from Doriprismatica stellata nudibranchs (Gastropoda, Nudibranchia), egg ribbons, and their dietary sponge Spongia cf. agaricina (Demospongiae, Dictyoceratida)
Hertzer, C.; Kehraus, S.; Böhringer, N.; Kaligis, F.; Bara, R.; Erpenbeck, D.; Wörheide, G.; Schäberle, T.F.; Wägele, H.; König, G.M.
Journal Article
2020Antimicrobial peptides from rat-tailed maggots of the drone fly Eristalis tenax show potent activity against multidrug-resistant gram-negative bacteria
Hirsch, R.; Wiesner, J.; Bauer, A.; Marker, A.; Vogel, H.; Hammann, P.E.; Vilcinskas, A.
Journal Article
2020Antimicrobial Susceptibility and Phylogenetic Relations in a German Cohort Infected with Mycobacterium abscessus
Wetzstein, N.; Kohl, T.A.; Schultze, T.G.; Andres, S.; Bellinghausen, C.; Hügel, C.; Kempf, V.A.J.; Lehn, A.; Hogardt, M.; Serve, H.; Vehreschild, M.J.G.T.; Wolf, T.; Niemann, S.; Maurer, F.P.; Wichelhaus, T.A.
Journal Article
2020Application of General Unified Threshold Models of Survival Models for Regulatory Aquatic Pesticide Risk Assessment Illustrated with an Example for the Insecticide Chlorpyrifos
Brock, T.; Arena, M.; Cedergreen, N.; Charles, S.; Duquesne, S.; Ippolito, A.; Klein, M.; Reed, M.; Teodorovic, I.; Brink, P.J. van den; Focks, A.
Journal Article
2020Application of Referencing Techniques in EEG-Based Recordings of Contact Heat Evoked Potentials (CHEPS)
Anders, M.; Anders, B.; Kreuzer, M.; Zinn, S.; Walter, C.
Journal Article
2020Aprotinin Inhibits SARS-CoV-2 Replication
Bojkova, D.; Bechtel, M.; McLaughlin, K.-M.; McGreig, J.E.; Klann, K.; Bellinghausen, C.; Rohde, G.; Jonigk, D.; Braubach, P.; Ciesek, S.; Münch, C.; Wass, M.N.; Michaelis, M.; Cinatl, J., Jr
Journal Article
2020Aquatic suspended particulate matter as source of eDNA for fish metabarcoding
Diaz, Cecilia; Wege, Franziska-Frederike; Tang, Cuong Q.; Crampton‑Platt, Alexandra; Rüdel, Heinz; Eilebrecht, Elke; Koschorreck, Jan
Journal Article
2020Aspergillus sydowii: Genome Analysis and Characterization of Two Heterologous Expressed, Non-redundant Xylanases
Brandt, S.C.; Ellinger, B.; Nguyen, T. van; Harder, S.; Schlüter, H.; Hahnke, R.L.; Rühl, M.; Schäfer, W.; Gand, M.
Journal Article
2020Assessment of SARS-CoV-2 Transmission on an International Flight and Among a Tourist Group
Hoehl, S.; Karaca, O.; Kohmer, N.; Westhaus, S.; Graf, J.; Goetsch, U.; Ciesek, S.
Journal Article
2020Attachment efficiency of nanomaterials to algae as an important criterion for ecotoxicity and grouping
Hund-Rinke, K.; Sinram, T.; Schlich, K.; Nickel, C.; Dickehut, H.P.; Schmidt, M.; Kühnel, D.
Journal Article
2020An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5
Huber, J.; Obata, M.; Gruber, J.; Akutsu, M.; Löhr, F.; Rogova, N.; Güntert, P.; Dikic, I.; Kirkin, V.; Komatsu, M.; Dötsch, V.; Rogov, V.V.
Journal Article
2020Author Correction: A new antibiotic selectively kills Gram-negative pathogens (Nature, 10.1038/s41586-019-1791-1)
Imai, Y.; Meyer, K.J.; Iinishi, A.; Favre-Godal, Q.; Green, R.; Manuse, S.; Caboni, M.; Mori, M.; Niles, S.; Ghiglieri, M.; Honrao, C.; Ma, X.; Guo, J.J.; Makriyannis, A.; Linares-Otoya, L.; Böhringer, N.; Wuisan, Z.G.; Kaur, H.; Wu, R.; Mateus, A.; Typas, A.; Savitski, M.M.; Espinoza, J.L.; O’Rourke, A.; Nelson, K.E.; Hiller, S.; Noinaj, N.; Schäberle, T.F.; d'Onofrio, A.; Lewis, K.
Journal Article
2020Bacteria associated with cockroaches: health risk or biotechnological opportunity?
Guzman, J.; Vilcinskas, A.
Journal Article
2020Bicistronic expression and differential localization of proteins in insect cells and Drosophila suzukii using picornaviral 2A peptides
Schwirz, J.; Yan, Y.; Franta, Z.; Schetelig, M.F.
Journal Article
2020Bildgebung bei der Psoriasisarthritis und Aspekte der röntgenologischen Progression
Baraliakos, X.; Kleyer, A.; Simon, D.; Köhm, M.; Ohrndorf, S.; Sewerin, P.
Journal Article
2020Bioavailability of silver from wastewater and planktonic food borne silver nanoparticles in the rainbow trout Oncorhynchus mykiss
Zeumer, Richard; Hermsen, Lara; Kägi, Ralf; Kühr, Sebastian; Knopf, Burkhard; Schlechtriem, Christian
Journal Article
2020Bioconcentration, metabolism and spatial distribution of 14C‐labelled laurate in the freshwater amphipod Hyalella Azteca
Raths, Johannes; Kühr, Sebastian; Schlechtriem, Christian
Journal Article
2020Biodegradation testing of volatile hydrophobic chemicals in water-sediment systems - Experimental developments and challenges
Shresta, Prasit; Meisterjahn, Boris; Hughes, Christopher B.; Mayer, Philipp; Birch, Heidi; Hennecke, Dieter
Journal Article
2020Biomagnification of ionizable organic compounds in rainbow trout Oncorhynchus mykiss
Mueller, Carolin; Trapp, Stefan; Polesel, Fabio; Kuehr, Sebastian; Schlechtriem, Christian
Journal Article
2020Biorelevant Two-Stage In Vitro Testing for rDCS Classification and in PBPK Modeling - Case Example Ritonavir
Fiolka, T.; Abeele, J. Van Den; Augustijns, P.; Arora, S.; Dressman, J.
Journal Article
2020Biotechnological Production of Odor-Active Methyl-Branched Aldehydes by a Novel α-Dioxygenase from Crocosphaera subtropica
Hammer, A.K.; Albrecht, F.; Hahne, F.; Jordan, P.; Fraatz, M.A.; Ley, J.; Geissler, T.; Schrader, J.; Zorn, H.; Buchhaupt, M.
Journal Article
2020Biotechnologically produced fucosylated oligosaccharides inhibit the binding of human noroviruses to their natural receptors
Derya, S.M.; Spiegel, H.; Hanisch, F.-G.; Morozov, V.; Schroten, H.; Jennewein, S.; Parschat, K.
Journal Article
2020Biotransformation Changes Bioaccumulation and Toxicity of Diclofenac in Aquatic Organisms
Fu, Qiuguo; Fedrizzi, Davide; Kosfeld, Verena; Schlechtriem, Christian; Ganz, Vera; Derrer, Samuel; Rentsch, Daniel; Hollender, Juliane
Journal Article
2020Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Moxifloxacin Hydrochloride
Charoo, N.A.; Abdallah, D.B.; Parveen, T.; Abrahamsson, B.; Cristofoletti, R.; Groot, D.W.; Langguth, P.; Parr, A.; Polli, J.E.; Mehta, M.; Shah, V.P.; Tajiri, T.; Dressman, J.
Journal Article
2020Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Cephalexin Monohydrate
Plöger, G.F.; Quizon, P.M.; Abrahamsson, B.; Cristofoletti, R.; Groot, D.W.; Parr, A.; Langguth, P.; Polli, J.E.; Shah, V.P.; Tajiri, T.; Mehta, M.U.; Dressman, J.
Journal Article
2020Bone Marrow Mononuclear Cells Activate Angiogenesis via Gap Junction-Mediated Cell-Cell Interaction
Kikuchi-Taura, A.; Okinaka, Y.; Takeuchi, Y.; Ogawa, Y.; Maeda, M.; Kataoka, Y.; Yasui, T.; Kimura, T.; Gul, S.; Claussen, C.; Boltze, J.; Taguchi, A.
Journal Article
2020Branched-chain fatty acids as mediators of the activation of hepatic peroxisome proliferator-activated receptor alpha by a fungal lipid extract
Maheshwari, G.; Ringseis, R.; Wen, G.; Gessner, D.K.; Rost, J.; Fraatz, M.A.; Zorn, H.; Eder, K.
Journal Article
2020Brief clinical evaluation of six high-throughput SARS-CoV-2 IgG antibody assays
Kohmer, N.; Westhaus, S.; Rühl, C.; Ciesek, S.; Rabenau, H.F.
Journal Article
2020Canakinumab for Treatment of Adult-Onset Still's Disease to Achieve Reduction of Arthritic Manifestation (CONSIDER): Phase II, randomised, double-blind, placebo-controlled, multicentre, investigator-initiated trial
Kedor, C.; Listing, J.; Zernicke, J.; Weiß, A.; Behrens, F.; Blank, N.; Henes, J.C.; Kekow, J.; Rubbert-Roth, A.; Schulze-Koops, H.; Seipelt, E.; Specker, C.; Feist, E.
Journal Article
2020Capnography monitoring of non‐anesthesiologist provided sedation during percutaneous endoscopic gastrostomy placement: A prospective, controlled, randomized trial
Peveling-Oberhag, J.; Michael, F.; Tal, A.; Welsch, C.; Vermehren, J.; Farnik, H.; Grammatikos, G.; Lange, C.; Walter, D.; Blumenstein, I.; Filmann, N.; Herrmann, E.; Albert, J.; Zeuzem, S.; Bojunga, J.; Friedrich-Rust, M.
Journal Article
2020Cell-Type Targeted NF-kappaB Inhibition for the Treatment of Inflammatory Diseases
Sehnert, B.; Burkhardt, H.; Dübel, S.; Voll, R.E.
Journal Article
2020Central encoding of the strength of intranasal chemosensory trigeminal stimuli in a human experimental pain setting
Lötsch, J.; Oertel, B.G.; Felden, L.; Nöth, U.; Deichmann, R.; Hummel, T.; Walter, C.
Journal Article
2020Ceramide synthase 5 deficiency aggravates dextran sodium sulfate-induced colitis and colon carcinogenesis and impairs T-cell activation
El-Hindi, K.; Brachtendorf, S.; Hartel, J.C.; Oertel, S.; Birod, K.; Trautmann, S.; Thomas, D.; Ulshöfer, T.; Weigert, A.; Utermöhlen, O.; Krönke, M.; Grösch, S.
Journal Article
2020Changes in the cervical microbiota of cervical cancer patients after primary radio-chemotherapy
Tsakmaklis, A.; Vehreschild, M.; Farowski, F.; Trommer, M.; Kohler, C.; Herter, J.; Marnitz, S.
Journal Article
2020Characteristics of contents in the upper gastrointestinal lumen after a standard high-calorie high-fat meal and implications for the in vitro drug product performance testing conditions
Pentafragka, C.; Vertzoni, M.; Dressman, J.; Symillides, M.; Goumas, K.; Reppas, C.
Journal Article
2020Characterization of the Nutritional Composition of a Biotechnologically Produced Oyster Mushroom and its Physiological Effects in Obese Zucker Rats
Maheshwari, G.; Gessner, D.K.; Meyer, S.; Ahlborn, J.; Wen, G.; Ringseis, R.; Zorn, H.; Eder, K.
Journal Article
2020Chemical starting matter for HNF4α ligand discovery and chemogenomics
Meijer, I.; Willems, S.; Ni, X.; Heering, J.; Chaikuad, A.; Merk, D.
Journal Article
2020Chemicals of emerging concern in marine specimens of the German Environmental Specimen Bank
Fliedner, Annette; Rüdel, Heinz; Dreyer, Annekatrin; Pirntke, Ulrike; Koschorreck, Jan
Journal Article
2020Chronic effects of wastewater-borne silver and titanium dioxide nanoparticles on the rainbow trout (Oncorhynchus mykiss)
Zeumer, Richard; Galhano, Victor; Monteiro, Marta S.; Kühr, Sebastian; Knopf, Burkhard; Meisterjahn, Boris; Soares, Amadeu M.V.M.; Loureiro, Susana; Lopes, Isabel; Schlechtriem, Christian
Journal Article
2020Clinical performance of different SARS‐CoV‐2 IgG antibody tests
Kohmer, N.; Westhaus, S.; Rühl, C.; Ciesek, S.; Rabenau, H.F.
Journal Article
2020Clostridioides difficile infections in the intensive care unit: a monocentric cohort study
Aguilar, R.C.; Salmanton-García, J.; Carney, J.; Böll, B.; Kochanek, M.; Jazmati, N.; Cornely, O.A.; Vehreschild, M.J.G.T.
Journal Article
2020Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics
Runfola, M.; Sestito, S.; Gul, S.; Chiellini, G.; Rapposelli, S.
Journal Article
2020Colonization with multi-drug-resistant organisms negatively impacts survival in patients with non-small cell lung cancer
Stratmann, J.A.; Lacko, R.; Ballo, O.; Shaid, S.; Gleiber, W.; Vehreschild, M.J.G.T.; Wichelhaus, T.; Reinheimer, C.; Göttig, S.; Kempf, V.A.J.; Kleine, P.; Stera, S.; Brandts, C.; Sebastian, M.; Koschade, S.
Journal Article
2020Combinatorial metabolic engineering in saccharomyces cerevisiae for the enhanced production of the fpp-derived sesquiterpene germacrene
Bröker, J.N.; Müller, B.; Prüfer, D.; Gronover, C.S.
Journal Article
2020Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispersion formulation of etravirine in the fed state
Litou, C.; Turner, D.B.; Holmstock, N.; Ceulemans, J.; Box, K.J.; Kostewicz, E.; Kuentz, M.; Holm, R.; Dressman, J.
Journal Article
2020Comparative analysis of phenotypic and genotypic antibiotic susceptibility patterns in Mycobacterium avium complex
Wetzstein, N.; Kohl, T.A.; Andres, S.; Schultze, T.G.; Geil, A.; Kim, E.; Biciusca, T.; Hügel, C.; Hogardt, M.; Lehn, A.; Vehreschild, M.J.G.T.; Wolf, T.; Niemann, S.; Maurer, F.P.; Wichelhaus, T.A.
Journal Article
2020Comparative proteome and metabolome analyses of latex-exuding and non-exuding Taraxacum koksaghyz roots provide insights into laticifer biology
Benninghaus, V.A.; Deenen, N. van; Müller, B.; Roelfs, K.-U.; Lassowskat, I.; Finkemeier, I.; Prüfer, D.; Schulze Gronover, C.
Journal Article
2020Comparison of Alternative Methods for Bioaccumulation Assessment: Scope and Limitations of In Vitro Depletion Assays with Rainbow Trout and Bioconcentration Tests in the Freshwater Amphipod Hyalella azteca
Kosfeld, Verena; Fu, Qiuguo; Ebersbach, Ina; Esser, Dana; Schauerte, Anna; Bischof, Ina; Hollender, Juliane; Schlechtriem, Christian
Journal Article
2020Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities
Teyra, J.; Ernst, A.; Singer, A.; Sicheri, F.; Sidhu, S.S.
Journal Article
2020Comprehensive Evaluation of Hepatitis E Serology and Molecular Testing in a Large Cohort
Anastasiou, O.E.; Thodou, V.; Berger, A.; Wedemeyer, H.; Ciesek, S.
Journal Article
2020Comprehensive evaluation of the metabolic effects of insect meal from Tenebrio molitor L. in growing pigs by transcriptomics, metabolomics and lipidomics
Meyer, S.; Gessner, D.K.; Braune, M.S.; Friedhoff, T.; Most, E.; Höring, M.; Liebisch, G.; Zorn, H.; Eder, K.; Ringseis, R.
Journal Article
2020Comprehensive platelet phenotyping supports the role of platelets in the pathogenesis of acute venous thromboembolism - results from clinical observation studies
Panova-Noeva, M.; Wagner, B.; Nagler, M.; Koeck, T.; Cate, V. ten; Prochaska, J.H.; Heitmeier, S.; Meyer, I.; Gerdes, C.; Laux, V.; Konstantinides, S.; Spronk, H.M.; Münzel, T.; Lackner, K.J.; Leineweber, K.; Cate, H. ten; Wild, P.S.
Journal Article
2020Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms
Chaikuad, A.; Pollinger, J.; Rühl, M.; Ni, X.; Kilu, W.; Heering, J.; Merk, D.
Journal Article
2020Computer-Aided Fragment Growing Strategies to Design Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase
Hefke, L.; Hiesinger, K.; Zhu, W.F.; Kramer, J.S.; Proschak, E.
Journal Article
2020Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids
Wiechmann, S.; Maisonneuve, P.; Grebbin, B.M.; Hoffmeister, M.; Kaulich, M.; Clevers, H.; Rajalingam, K.; Kurinov, I.; Farin, H.F.; Sicheri, F.; Ernst, A.
Journal Article
2020Correction to: Sustained improvement in work outcomes in employed patients with rheumatoid arthritis during 2 years of adalimumab therapy: An observational cohort study
Behrens, F.; Tony, H.-P.; Koehm, M.; Schwaneck, E.C.; Gnann, H.; Greger, G.; Burkhardt, H.; Schmalzing, M.
Journal Article
2020COVID-19 - eine Multiorganerkrankung stellt das Gesundheitssystem auf die Probe
Klippenstein, V.; Ciesek, S.; Riemann, J.F.
Journal Article
2020COVID-19-Related Coagulopathy - Is Transferrin a Missing Link?
McLaughlin, K.-M.; Bechtel, M.; Bojkova, D.; Münch, C.; Ciesek, S.; Wass, M.N.; Michaelis, M.; Cinatl, J.
Journal Article
2020CRISPR/Cas9 mediated disruption of the white gene leads to pigmentation deficiency and copulation failure in Drosophila suzukii
Yan, Y.; Ziemek, J.; Schetelig, M.F.
Journal Article
2020Current projection methods-induced biases at subgroup detection for machine-learning based data-analysis of biomedical data
Lötsch, J.; Ultsch, A.
Journal Article
2020Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer
Kesavan, R.; Frömel, T.; Zukunft, S.; Laban, H.; Geyer, A.; Naeem, Z.; Heidler, J.; Wittig, I.; Elwakeel, E.; Brüne, B.; Weigert, A.; Popp, R.; Fleming, I.
Journal Article
2020A data science approach to the selection of most informative readouts of the human intradermal capsaicin pain model to assess pregabalin effects
Lötsch, J.; Walter, C.; Zunftmeister, M.; Zinn, S.; Wolters, M.; Ferreiros, N.; Rossmanith, T.; Oertel, B.G.; Geisslinger, G.
Journal Article
2020A data science-based analysis of seasonal patterns in outpatient presentations due to olfactory dysfunction
Lötsch, J.; Hummel, T.
Journal Article
2020Data-science-based subgroup analysis of persistent pain during 3 years after breast cancer surgery: A prospective cohort study
Lötsch, J.; Ultsch, A.; Kalso, E.
Journal Article
2020Dependency of Toxicity on Time and Dose in Fish Life-Cycle Tests - Effects and Effect Thresholds of Tamoxifen Citrate to Different Life-Stages of Zebrafish in Variable Exposure Scenarios
Kroesen, Sven
: Schäfers, Christoph; Meyer, Elisabeth Irmgard
Dissertation
2020Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
Runfola, M.; Sestito, S.; Bellusci, L.; Pietra, V. la; D'Amore, V.M.; Kowalik, M.A.; Chiellini, G.; Gul, S.; Perra, A.; Columbano, A.; Marinelli, L.; Novellino, E.; Rapposelli, S.
Journal Article
2020Design, Synthesis, and Structure - Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase
Hiesinger, K.; Kramer, J.S.; Beyer, S.; Eckes, T.; Brunst, S.; Flauaus, C.; Wittmann, S.K.; Weizel, L.; Kaiser, A.; Kretschmer, S.B.M.; George, S.; Angioni, C.; Heering, J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Schmidtko, A.; Pogoryelov, D.; Pfeilschifter, J.; Hofmann, B.; Steinhilber, D.; Schwalm, S.; Proschak, E.
Journal Article
2020Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics
Ayobahan, Steve U.; Eilebrecht, Sebastian; Baumann, Lisa; Teigeler, Matthias; Hollert, Henner; Kalkhof, Stefan; Eilebrecht, Elke; Schäfers, Christoph
Journal Article
2020Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine
Lothert, K.; Offersgaard, A.F.; Pihl, A.F.; Mathiesen, C.K.; Jensen, T.B.; Alzua, G.P.; Fahnøe, U.; Bukh, J.; Gottwein, J.M.; Wolff, M.W.
Journal Article
2020Development of a method to determine the bioaccumulation of manufactured nanomaterials in filtering organisms (Bivalvia). Final Report
Schlechtriem, Christian; Knopf, Burkhard; Kühr, Sebastian; Meisterjahn, Boris; Schröder, Nicola
Report
2020Development of a solventless stir bar sorptive extraction/thermal desorption large volume injection capillary gas chromatographic-mass spectrometric method for ultra-trace determination of pyrethroids pesticides in river and tap water samples
Sargazi, Mona; Bücking, Mark; Kaykhaii, Massoud
Journal Article
2020Development of a test method for transformation of veterinary pharmaceuticals and biocides in anaerobic liquid manure
Junker, Thomas; Atorf, Cornelia; Berkner, Silvia; Düring, Rolf-Alexander; Hennecke, Dieter; Herrchen, Monika; Konradi, Sabine; Merrettig-Bruns, Ute; Römbke, Jörg; Wagner, Julia; Weinfurtner, Karlheinz
Journal Article
2020Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells
Basavarajappa, D.; Uebbing, S.; Kreiss, M.; Lukic, A.; Suess, B.; Steinhilber, D.; Samuelsson, B.; Rådmark, O.
Journal Article
2020Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms
Maculins, T.; Garcia-Pardo, J.; Skenderovic, A.; Gebel, J.; Putyrski, M.; Vorobyov, A.; Busse, P.; Varga, G.; Kuzikov, M.; Zaliani, A.; Rahighi, S.; Schaeffer, V.; Parnham, M.J.; Sidhu, S.S.; Ernst, A.; Dötsch, V.; Akutsu, M.; Dikic, I.
Journal Article
2020Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine
Putyrski, M.; Vakhrusheva, O.; Bonn, F.; Guntur, S.; Vorobyov, A.; Brandts, C.; Dikic, I.; Ernst, A.
Journal Article
2020Dissolution behavior of various drugs in different FaSSIF versions
Klumpp, L.; Leigh, M.; Dressman, J.
Journal Article
2020Dissolution testing of modified release products with biorelevant media: An OrBiTo ring study using the USP apparatus III and IV
Reppas, C.; Vrettos, N.-N.; Dressman, J.; Andreas, C.J.; Miyaji, Y.; Brown, J.; Etherson, K.; Hanley, S.; Karkossa, F.; Karlsson, E.; Klein, S.; Maier, G.-M.; McAllister, M.; Mistry, N.; Rosenblatt, K.; Schäfer, K.J.; Smith, K.L.; Tomaszewska, I.; Williams, J.; Winge, F.; Vertzoni, M.
Journal Article
2020Distribution Optimization: An evolutionary algorithm to separate Gaussian mixtures
Lerch, F.; Ultsch, A.; Lötsch, J.
Journal Article
2020The disturbed iron phenotype of tumor cells and macrophages in renal cell carcinoma influences tumor growth
Schnetz, M.; Meier, J.K.; Rehwald, C.; Mertens, C.; Urbschat, A.; Tomat, E.; Akam, E.A.; Baer, P.; Roos, F.C.; Brüne, B.; Jung, M.
Journal Article
2020Does concomitant methotrexate confer clinical benefits in patients treated with prior biologic therapy?
Schmalzing, M.; Behrens, F.; Schwaneck, E.C.; Koehm, M.; Greger, G.; Gnann, H.; Burkhardt, H.; Tony, H.-P.
Journal Article
2020Does Light Color Temperature Influence Aspects of Oviposition by the Black Soldier Fly (Diptera: Stratiomyidae)?
Klüber, P.; Bakonyi, D.; Zorn, H.; Rühl, M.
Journal Article
2020Donated stool for faecal microbiota transplantation is not a drug, but guidance and regulation are needed
Keller, J.J.; Vehreschild, M.J.G.T.; Hvas, C.L.; Jørgensen, S.M.D.; Kupcinskas, J.; Link, A.; Mulder, C.J.J.; Goldenberg, S.D.; Arasaradnam, R.; Sokol, H.; Gasbarrini, A.; Hoegenauer, C.; Terveer, E.M.; Kuijper, E.J.; Arkkila, P.
Journal Article
2020Dual Farnesoid X Receptor/Soluble Epoxide Hydrolase Modulators Derived from Zafirlukast
Schierle, S.; Helmstädter, M.; Schmidt, J.; Hartmann, M.; Horz, M.; Kaiser, A.; Weizel, L.; Heitel, P.; Proschak, A.; Hernandez-Olmos, V.; Proschak, E.; Merk, D.
Journal Article
2020The dual FXa/thrombin inhibitor SATI prevents fibrin and platelet deposition in hypercoagulant rats
López, M.; Heitmeier, S.; Laux, V.; Nowak, G.
Journal Article
2020Dual soluble epoxide hydrolase inhibitor/PPAR-γ agonist attenuates renal fibrosis
Stavniichuk, A.; Hye Khan, M.A.; Yeboah, M.M.; Chesnik, M.A.; Jankiewicz, W.K.; Hartmann, M.; Blöcher, R.; Kircher, T.; Savchuk, O.; Proschak, E.; Imig, J.D.
Journal Article
2020An economic dilemma between molecular weapon systems may explain an arachno-atypical venom in wasp spiders (Argiope bruennichi)
Lüddecke, T.; von Reumont, B.M.; Förster, F.; Billion, A.; Timm, T.; Lochnit, G.; Vilcinskas, A.; Lemke, S.
Journal Article
2020Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis
Christodoulou-Vafeiadou, E.; Geka, C.; Ntari, L.; Kranidioti, K.; Argyropoulou, E.; Meier, F.; Armaka, M.; Mourouzis, I.; Pantos, C.; Rouchota, M.; Loudos, G.; Denis, M.C.; Karagianni, N.; Kollias, G.
Journal Article
2020Efficient inactivation of pseudotyped HIV-based lentiviral vectors and infectious HIV
Kriesel, F.; Stegmann, L.; Ciesek, S.; Kaderali, L.; Baldauf, H.-M.
Journal Article
2020The Emergency Response Capacity of Plant-Based Biopharmaceutical Manufacturing-What It Is and What It Could Be
Tusé, D.; Nandi, S.; McDonald, K.A.; Buyel, J.F.
Review
2020The Emerging Therapeutic Potential of Nitro Fatty Acids and Other Michael Acceptor-Containing Drugs for the Treatment of Inflammation and Cancer
Piesche, M.; Roos, J.; Kühn, B.; Fettel, J.; Hellmuth, N.; Brat, C.; Maucher, I.V.; Awad, O.; Matrone, C.; Comerma Steffensen, S.G.; Manolikakes, G.; Heinicke, U.; Zacharowski, K.D.; Steinhilber, D.; Maier, T.J.
Journal Article
2020The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells
Pflüger-Müller, B.; Oo, J.A.; Heering, J.; Warwick, T.; Proschak, E.; Günther, S.; Looso, M.; Rezende, F.; Fork, C.; Geisslinger, G.; Thomas, D.; Gurke, R.; Steinhilber, D.; Schulz, M.; Leisegang, M.S.; Brandes, R.P.
Journal Article
2020Enhancing the Heterologous Fructosyltransferase Activity of Kluyveromyces lactis: Developing a Scaled-Up Process and Abolishing Invertase by CRISPR/Cas9 Genome Editing
Burghardt, J.P.; Fan, R.; Baas, M.; Eckhardt, D.; Gerlach, D.; Czermak, P.
Journal Article
2020Environmental hazard testing of nanobiomaterials
Amorim, M.J.B.; Fernández-Cruz, M.L.; Hund-Rinke, K.; Scott-Fordsmand, J.J.
Journal Article
2020Epidemiological screening of captive salamanders reveals current absence of batrachochytrium salamandrivorans in private collections throughout the federal state of Hesse (Germany)
Jung, L.; Dusek, J.; Lüddecke, T.; Schulz, V.; Maier-Sam, K.; Habich, L.; Mosebach, A.; Lierz, M.; Ziemek, H.-P.
Journal Article
2020Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testing and physiologically-based population pharmacokinetic modeling. Case example: Naproxen
Loisios-Konstantinidis, I.; Cristofoletti, R.; Fotaki, N.; Turner, D.B.; Dressman, J.
Journal Article
2020Establishment and Characterization of a Unilateral UV-Induced Photoreceptor Degeneration Model in the C57Bl/6J Mouse
Meer, A.-M. van der; Berger, T.; Müller, F.; Foldenauer, A.C.; Johnen, S.; Walter, P.
Journal Article
2020Ether lipid and sphingolipid expression patterns are estrogen receptor-dependently altered in breast cancer cells
Hahnefeld, L.; Gruber, L.; Schömel, N.; Fischer, C.; Mattjus, P.; Gurke, R.; Beretta, M.; Ferreirós, N.; Geisslinger, G.; Wegner, M.-S.
Journal Article
2020European medicinal leeches - New roles in modern medicine
Lemke, S.; Vilcinskas, A.
Journal Article
2020Evaluation of Differences in Dosage Form Performance of Generics Using BCS-Based Biowaiver Specifications and Biopharmaceutical Modeling
Hofsäss, M.A.; Dressman, J.
Journal Article
2020Evaluation of Hydrogen Peroxide Fumigation and Heat Treatment for Standard Emergency Arthropod Inactivation in BSL-3 Insectaries
Häcker, I.; Koller, R.; Eichner, G.; Martin, J.; Liapi, E.; Rühl, J.; Rehling, T.; Schetelig, M.F.
Journal Article
2020Evaluation of potential environmental toxicity of polymeric nanomaterials and surfactants
Hering, Indra; Eilebrecht, Elke; Parnham, Michael J.; Günday-Türeli, Nazende; Türeli, Akif Emre; Weiler, Marc; Schäfers, Christoph; Fenske, Martina; Wacker, Matthias G.
Journal Article
2020Evaluation of the risk for soil organisms under real conditions
Toschki, Andreas; Hammers-Wirtz, Monika; Poßberg, Claudia; Ross-Nickoll, Martina; Schäffer, Andreas; Schmidt, Burkhard; Scholz Starke, Björn; Römbke, Jörg; Scheffzyk, Adam; Klein, Michael; Hommen, Udo
Report
2020Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China
Ciesek, Sandra
Journal Article
2020Exercise-Induced Changes in Bioactive Lipids Might Serve as Potential Predictors of Post-Exercise Hypotension. A Pilot Study in Healthy Volunteers
Wolters, M.C.; Schmetzer, J.; Möser, C.V.; Hahnefeld, L.; Angioni, C.; Thomas, D.; Ferreirós, N.; Geisslinger, G.; Niederberger, E.
Journal Article
2020Exploring CYP2J2: Lipid mediators, inhibitors and therapeutic implications
Sisignano, M.; Steinhilber, D.; Parnham, M.J.; Geisslinger, G.
Journal Article
2020Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples
Bajerski, F.; Bürger, A.; Glasmacher, B.; Keller, E.R.J.; Müller, K.; Mühldorfer, K.; Nagel, M.; Rüdel, H.; Müller, T.; Schenkel, J.; Overmann, J.
Journal Article
2020Fast, Precise, and Reliable Multiplex Detection of Potato Viruses by Loop-Mediated Isothermal Amplification
Edgü, G.; Freund, L.J.; Hartje, S.; Tacke, E.; Hofferbert, H.-R.; Twyman, R.M.; Noll, G.A.; Muth, J.; Prüfer, D.
Journal Article
2020Fate of acrylamide during coffee roasting and in vitro digestion assessed with carbon 14- and carbon 13-labeled materials
Badoud, Flavia; Göckener, Bernd; Severin, Kevin; Ernest, Marion; Romero, Roman; Alzieu, Thibaut; Glabasnia, Arne; Hamel, Jonas; Bücking, Mark; Delatour, Thierry
Journal Article
2020Fate of Chlorpropham during High-Temperature Processing of Potatoes
Göckener, Bernd; Kotthoff, Matthias; Kling, Hans-Willi; Bücking, Mark
Journal Article
2020Fecal Microbiota Transfer
Stallmach, A.; Steube, A.; Grunert, P.; Hartmann, M.; Biehl, L.M.; Vehreschild, M.J.G.T.
Journal Article
2020A field study in support of the monitoring of priority substances in German freshwater fish: Derivation of fillet-to-whole fish conversion factors
Rüdel, Heinz; Radermacher, Georg; Fliedner, Annette; Lohmann, Nina; Duffek, Anja
Journal Article
2020First Structure-Activity Relationship Study of Potent BLT2 Agonists as Potential Wound-Healing Promoters
Hernandez-Olmos, V.; Heering, J.; Planz, V.; Liu, T.; Kaps, A.; Rajkumar, R.; Gramzow, M.; Kaiser, A.; Schubert-Zsilavecz, M.; Parnham, M.J.; Windbergs, M.; Steinhilber, D.; Proschak, E.
Journal Article
2020Flow cytometry-based system for screening of lignin peroxidase mutants with higher oxidative stability
Ilić Đurđić, K.; Ece, S.; Ostafe, R.; Vogel, S.; Balaž, A.M.; Schillberg, S.; Fischer, R.; Prodanovic, R.
Journal Article
2020Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2019
 
Annual Report
2020From cancer to immune-mediated diseases and tolerance induction: Lessons learned from immune oncology and classical anti-cancer treatment
Klöß, Stephan; Dehmel, Susann; Braun, Armin; Parnham, Michael J.; Koehl, Ulrike; Schiffmann, Susanne
Journal Article
2020Das frühe Erkennen postoperativen Nierenversagens nach offener thorakoabdomineller Aortenchirurgie: Eine multizentrische Observationsstudie (Nephrocheck™-TAAA-Trial)
Gombert, A.; Oberhuber, A.; Greiner, A.; Eierhoff, T.; Heine, B.; Omran, S.; Frese, J.; Doukas, P.; Foldenauer, A.-C.; Jacobs, M.J.
Journal Article
2020Frühe, zeitlich begrenzte intensive immunmodulatorische Therapie zum Erreichen einer Remission in Psoriasis Arthritis
Köhm, M.
Journal Article
2020Function of Cathepsin K in the Central Nervous System of Male Mice is Independent of its Role in the Thyroid Gland
Dauth, S.; Rakov, H.; Sîrbulescu, R.F.; Ilieş, I.; Weber, J.; Batbajar Dugershaw, B.; Braun, D.; Rehders, M.; Wirth, E.K.; Führer, D.; Schweizer, U.; Brix, K.
Journal Article
2020Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme
Marbach-Breitrück, E.; Kutzner, L.; Rothe, M.; Gurke, R.; Schreiber, Y.; Reddanna, P.; Schebb, N.-H.; Stehling, S.; Wieler, L.H.; Heydeck, D.; Kuhn, H.
Journal Article
2020Functional characterization of the Drosophila suzukii pro-apoptotic genes reaper, head involution defective and grim
Jaffri, S.A.; Yan, Y.; Schwirz, J.; Schetelig, M.F.
Journal Article
2020The Fundamental Clustering and Projection Suite (FCPS)
Ultsch, A.; Lötsch, J.
Journal Article
2020Gene expression variability between randomly and targeted transgene integration events in tobacco suspension cell lines
Kirchhoff, Janina; Schiermeyer, Andreas; Schneider, Katja; Fischer, Rainer; Ainley, W. Michael; Webb, Steven R.; Schinkel, Helga; Schillberg, Stefan
Journal Article
2020Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups
Assmann, G.; Köhm, M.; Schuster, V.; Behrens, F.; Mössner, R.; Magnolo, N.; Oji, V.; Burkhardt, H.; Hüffmeier, U.
Journal Article
2020Global occurrence, chemical properties, and ecological impacts of e-wastes (IUPAC technical report)
Purchase, Diane; Abbasi, Golnoush; Bisschop, Lieselot; Chatterjee, Debashish; Ekberg, Christian; Ermolin, Mikhail; Fedotov, Petr; Garelick, Hemda; Isimekhai, Khadijah; Kandile, Nadia G.; Lundström, Mari; Matharu, Avtar; Miller, Bradley W.; Pineda, Antonio; Popoola, Oluseun E.; Retegan, Teodora; Ruedel, Heinz; Serpe, Angela; Sheva, Yehuda; Surati, Kiran R.; Walsh, Fiona; Wilson, Benjamin P.; Wong, Ming Hung
Journal Article
2020Glucagon-like peptide 1 levels predict cardiovascular risk in patients with acute myocardial infarction
Kahles, F.; Rückbeil, M.V.; Mertens, R.W.; Foldenauer, A.C.; Arrivas, M.C.; Moellmann, J.; Lebherz, C.; Biener, M.; Giannitsis, E.; Katus, H.A.; Marx, N.; Lehrke, M.
Journal Article
2020The gram-positive bacterium Leuconostoc pseudomesenteroides shows insecticidal activity against drosophilid and aphid pests
Hiebert, N.; Kessel, T.; Skaljac, M.; Spohn, M.; Vilcinskas, A.; Lee, K.-Z.
Journal Article
2020Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication
Klann, K.; Bojkova, D.; Tascher, G.; Ciesek, S.; Münch, C.; Cinatl, J.
Journal Article
2020The gut and feed residue microbiota changing during the rearing of Hermetia illucens larvae
Cifuentes, Y.; Glaeser, S.P.; Mvie, J.; Bartz, J.-O.; Müller, A.; Gutzeit, H.O.; Vilcinskas, A.; Kämpfer, P.
Journal Article
2020Halogenation‐Guided Chemical Screening Provides Insight into Tjipanazole Biosynthesis by the Cyanobacterium Fischerella ambigua
Chilczuk, T.; Schäberle, T.F.; Vahdati, S.; Mettal, U.; El Omari, M.; Enke, H.; Wiese, M.; König, G.M.; Niedermeyer, T.H.J.
Journal Article
2020A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial
Mease, P.J.; Smolen, J.S.; Behrens, F.; Nash, P.; Liu Leage, S.; Li, L.; Tahir, H.; Gooderham, M.; Krishnan, E.; Liu-Seifert, H.; Emery, P.; Pillai, S.G.; Helliwell, P.S.
Journal Article
2020Health Assessment Questionnaire-Disability Index (HAQ-DI) use in modelling disease progression in diffuse cutaneous systemic sclerosis: an analysis from the EUSTAR database
Allanore, Y.; Bozzi, S.; Terlinden, A.; Huscher, D.; Amand, C.; Soubrane, C.; Siegert, E.; Czirják, L.; Carreira, P.E.; Hachulla, E.; Zanatta, E.; Li, M.; Airò, P.; Mendoza, F.A.; Rosato, E.; Distler, O.; Köhm, M. et al.
Journal Article
2020HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies
Heinen, S.; Schulze, N.; Franke, B.; Klein, F.; Lehmann, C.; Vehreschild, M.J.G.T.; Gloistein, C.; Stecher, M.; Vehreschild, J.J.
Journal Article
2020High Glucosylceramides and Low Anandamide Contribute to Sensory Loss and Pain in Parkinson's Disease
Klatt-Schreiner, K.; Valek, L.; Kang, J.-S.; Khlebtovsky, A.; Trautmann, S.; Hahnefeld, L.; Schreiber, Y.; Gurke, R.; Thomas, D.; Wilken-Schmitz, A.; Wicker, S.; Auburger, G.; Geisslinger, G.; Lötsch, J.; Pfeilschifter, W.; Djaldetti, R.; Tegeder, I.
Journal Article
2020A high-throughput HIV-1 drug screening platform, based on lentiviral vectors and compatible with biosafety level-1
Ellinger, B.; Pohlmann, D.; Woens, J.; Jäkel, F.M.; Reinshagen, J.; Stocking, C.; Prassolov, V.S.; Fehse, B.; Riecken, K.
Journal Article
2020Highlights of the 12th Wartburg Symposium on Flavor Chemistry & Biology
Zorn, H.; Hofmann, T.; Dawid, C.
Journal Article
2020Histone deacetylation inhibitors as modulators of regulatory T cells
Knethen, A. von; Heinicke, U.; Weigert, A.; Zacharowski, K.; Brüne, B.
Journal Article
2020Human biomonitoring of per- and polyfluoroalkyl substances in German blood plasma samples from 1982 to 2019
Göckener, Bernd; Weber, Till; Rüdel, Heinz; Bücking, Mark; Kolossa-Gehring, Marike
Journal Article
2020Human iPSC-Derived Blood-Brain Barrier Models: Valuable Tools for Preclinical Drug Discovery and Development?
Appelt-Menzel, Antje; Oerter, Sabrina; Mathew, Sanjana; Haferkamp, Undine; Hartmann, Carla; Jung, Matthias; Neuhaus, Winfried; Pless, Ole
Journal Article
2020Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis
Fuhrmann, D.C.; Mondorf, A.; Beifuß, J.; Jung, M.; Brüne, B.
Journal Article
2020Identification and molecular analysis of interaction sites in the MtSEO-F1 protein involved in forisome assembly
Rose, J.; Visser, F.; Müller, B.; Senft, M.; Groscurth, S.; Sicking, K.F.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Journal Article
2020Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign
Linciano, P.; Cullia, G.; Borsari, C.; Santucci, M.; Ferrari, S.; Witt, G.; Gul, S.; Kuzikov, M.; Ellinger, B.; Santarem, N.; Cordeiro da Silva, A.; Conti, P.; Bolognesi, M.L.; Roberti, M.; Prati, F.; Bartoccini, F.; Retini, M.; Piersanti, G.; Cavalli, A.; Goldoni, L.; Bertozzi, S.M.; Bertozzi, F.; Brambilla, E.; Rizzo, V.; Piomelli, D.; Pinto, A.; Bandiera, T.; Costi, M.P.
Journal Article
2020Identification of entomopathogenic bacteria associated with the invasive pest Drosophila suzukii in infested areas of Germany
Hiebert, N.; Carrau, T.; Bartling, M.; Vilcinskas, A.; Lee, K.-Z.
Journal Article
2020Identification, cloning, expression and functional interrogation of the biosynthetic pathway of the polychlorinated triphenyls ambigol A-C from Fischerella ambigua 108b
Duell, E.R.; Milzarek, T.M.; El Omari, M.; Linares-Otoya, L.J.; Schäberle, T.F.; König, G.M.; Gulder, T.A.M.
Journal Article
2020IL-36 family cytokines in protective versus destructive inflammation
Han, Y.; Huard, A.; Mora, J.; da Silva, P.; Brüne, B.; Weigert, A.
Journal Article
2020Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model
Sirait-Fischer, E.; Olesch, C.; Fink, A.F.; Berkefeld, M.; Huard, A.; Schmid, T.; Takeda, K.; Brüne, B.; Weigert, A.
Journal Article
2020Impact of Clostridioides difficile infection on the outcome of patients receiving a hematopoietic stem cell transplantation
Weber, S.; Scheich, S.; Magh, A.; Wolf, S.; Enßle, J.C.; Brunnberg, U.; Reinheimer, C.; Wichelhaus, T.A.; Kempf, V.A.J.; Kessel, J.; Vehreschild, M.J.G.T.; Serve, H.; Bug, G.; Steffen, B.; Hogardt, M.
Journal Article
2020Impact of hyperhomocysteinemia and different dietary interventions on cognitive performance in a knock-in mouse model for alzheimer's disease
Nieraad, H.; de Bruin, N.; Arne, O.; Hofmann, M.C.J.; Schmidt, M.; Saito, T.; Saido, T.C.; Gurke, R.; Schmidt, D.; Till, U.; Parnham, M.J.; Geisslinger, G.
Journal Article
2020Impact of simulated sunlight on the degradation of pendimethalin in surface water in a scale‑up experiment in accordance to OECD TG 309
Hennecke, Dieter; Hassink, Jan; Klein, Judith; Kruse, Mike
Journal Article
2020Impact of wastewater-borne nanoparticles of silver and titanium dioxide on the swimming behaviour and biochemical markers of Daphnia magna: An integrated approach
Galhano, Victor; Hartmann, Sarah; Monteiro, Marta S.; Zeumer, Richard; Mozhayeva, Darya; Steinhoff, Benedikt; Müller, Katharina; Prenzel, Kirsten; Kunze, Jan; Kuhnert, Klaus-Dieter; Schönherr, Holger; Engelhard, Carsten; Schlechtriem, Christian; Loureiro, Susana; Soares, Amadeu M.V.M.; Witte, Klaudia; Lopes, Isabel
Journal Article
2020Implementation of lipidomics in clinical routine: Can fluoride/citrate blood sampling tubes improve preanalytical stability?
Hahnefeld, L.; Gurke, R.; Thomas, D.; Schreiber, Y.; Schäfer, S.M.G.; Trautmann, S.; Snodgrass, I.F.; Kratz, D.; Geisslinger, G.; Ferreiros, N.
Journal Article
2020Implementierung eines Betriebskonzeptes in einer HNO-Klinik im Rahmen der SARS-CoV-2-Pandemie
Weiss, R.; Loth, A.; Guderian, D.; Diensthuber, M.; Kempf, V.; Hack, D.; Wicker, S.; Ciesek, S.; Graf, J.; Stöver, T.; Leinung, M.
Journal Article
2020Improved transgenic sexing strains for genetic control of the Australian sheep blow fly Lucilia cuprina using embryo-specific gene promoters
Yan, Y.; Williamson, M.E.; Davis, R.J.; Andere, A.A.; Picard, C.J.; Scott, M.J.
Journal Article
2020Improvement in oxidative stability of versatile peroxidase by flow cytometry-based high-throughput screening system
Ilić Đurđić, K.; Ece, S.; Ostafe, R.; Vogel, S.; Schillberg, S.; Fischer, R.; Prodanović, R.
Journal Article
2020Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids
Buck, J.; Mueller, D.; Mettal, U.; Ackermann, M.; Grisch-Chan, H.M.; Thöny, B.; Zumbuehl, A.; Huwyler, J.; Witzigmann, D.
Journal Article
2020In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o
Blum, L.; Gul, S.; Ulshöfer, T.; Henke, M.; Krieg, R.; Berneburg, I.; Thomas, D.; Trautmann, S.; Kurz, J.; Geyer, J.; Geisslinger, G.; Becker, K.; Parnham, M.J.; Schiffmann, S.
Journal Article
2020Incorporation of HPMCAS during loading of glibenclamide onto mesoporous silica improves dissolution and inhibits precipitation
Price, D.J.; Nair, A.; Becker-Baldus, J.; Glaubitz, C.; Kuentz, M.; Dressman, J.; Saal, C.
Journal Article
2020Incretin combination therapy for the treatment of non-alcoholic steatohepatitis
Kannt, A.; Madsen, A.N.; Kammermeier, C.; Elvert, R.; Klöckener, T.; Bossart, M.; Haack, T.; Evers, A.; Lorenz, K.; Hennerici, W.; Rocher, C.; Böcskei, Z.; Guillemot, J.-C.; Mikol, V.; Pattou, F.; Staels, B.; Wagner, M.
Journal Article
2020Individual therapeutic DAS28-dcrit responses differentiate between effectiveness of rheumatoid arthritis therapies and reflect patient-reported outcomes
Koehm, M.; McIntosh, M.J.; Hofmann, M.W.; Abraham, V.; Gabay, C.; Choy, E.H.; Kavanaugh, A.; Burkhardt, H.; Behrens, F.
Journal Article
2020Industriebeispiele und Anwendungsbereiche
Schwarz, Thomas; Gürtler, Christoph; Müller, Torsten; Mihalcea, Christophe; Burton, Freya; Conrado, Robert; Simpson, Sean; Maru, Biniam T; Munasinghe, Pradeep C; Jones, Shawn W.; Tracy, Bryan P.; Machielsen, Ronnie; Gordon, Ross; Pant, Deepak; Bulut, Metin; Wever, Helen de; Kensy, Frank; Verseck, Stefan; Janke, Christian
Book Article
2020Influence of different definitions of central venous catheter–related bloodstream infections on epidemiological parameters in cancer patients
Schalk, E.; Vehreschild, M.J.G.T.; Biehl, L.M.
Journal Article
2020Influence of glycosphingolipids on cancer cell energy metabolism
Schömel, N.; Geisslinger, G.; Wegner, M.-S.
Journal Article
2020Influence of soil on the uptake of perfluoroalkyl acids by lettuce: A comparison between a hydroponic study and a field study
Felizeter, S.; Jürling, H.; Kotthoff, M.; Voogt, P. de; McLachlan, M.S.
Journal Article
2020The influenza virus NS1A binding protein gene modulates macrophages response to cytokines and phagocytic potential in inflammation
Hotter, G.; Mastora, C.; Jung, M.; Brüne, B.; Carbonell, T.; Josa, C.; Pérez-Calvo, J.I.; Cruzado, J.M.; Guiteras, R.; Sola, A.
Journal Article
2020Inhibition of HDAC Enzymes Contributes to Differential Expression of Pro-Inflammatory Proteins in the TLR-4 Signaling Cascade
Weiss, U.; Möller, M.; Husseini, S.A.; Manderscheid, C.; Häusler, J.; Geisslinger, G.; Niederberger, E.
Journal Article
2020Inhibition of histone acetylation and deacetylation enzymes affects longevity, development, and fecundity in the pea aphid (Acyrthosiphon pisum)
Kirfel, P.; Skaljac, M.; Grotmann, J.; Kessel, T.; Seip, M.; Michaelis, K.; Vilcinskas, A.
Journal Article
2020Innovative Imaging Technique for Visualization of Vascularization and Established Methods for Detection of Musculoskeletal Inflammation in Psoriasis Patients
Köhm, M.; Zerweck, L.; Ngyuen, P.-H.; Burkhardt, H.; Behrens, F.
Journal Article
2020Innovative Optical-Sensing Technology for the Online Fouling Characterization of Silicon Carbide Membranes during the Treatment of Oily Water
Ebrahimi, M.; Schmidt, A.A.; Kaplan, C.; Schmitz, O.; Czermak, P.
Journal Article
2020The insect antimicrobial peptide cecropin A disrupts uropathogenic Escherichia coli biofilms
Kalsy, M.; Tonk, M.; Hardt, M.; Dobrindt, U.; Zdybicka-Barabas, A.; Cytrynska, M.; Vilcinskas, A.; Mukherjee, K.
Journal Article
2020Insect Biotechnology. Insects as a Resource
Vilcinskas, Andreas
Book Article
2020Insektizide in Böden unterschiedlicher Bewirtschaftung
Leisner, Jörg; Guhl, Barbara; Hindersmann, Benjamin; Göckener, Bernd
Journal Article
2020Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications
Harberts, J.; Haferkamp, U.; Haugg, S.; Fendler, C.; Lam, D.; Zierold, R.; Pless, O.; Blick, R.H.
Journal Article
2020Intestinale Mikrobiota - Prädiktor für Mortalität nach Stammzelltransplantation
Vehreschild, M.J.G.T.; Tsakmaklis, A.; Nitschmann, S.
Journal Article
2020Intravenous Bone Marrow Mononuclear Cells Transplantation in Aged Mice Increases Transcription of Glucose Transporter 1 and Na+/K+-ATPase at Hippocampus Followed by Restored Neurological Functions
Takeuchi, Y.; Okinaka, Y.; Ogawa, Y.; Kikuchi-Taura, A.; Kataoka, Y.; Gul, S.; Claussen, C.; Boltze, J.; Taguchi, A.
Journal Article
2020Investigation of Dissolution Performance of Hard Gelatin Capsule Products Using Various Sinkers
Mansuroglu, Y.; Dressman, J.
Journal Article
2020The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma
Rehwald, C.; Schnetz, M.; Urbschat, A.; Mertens, C.; Meier, J.K.; Bauer, R.; Baer, P.; Winslow, S.; Roos, F.C.; Zwicker, K.; Huard, A.; Weigert, A.; Brüne, B.; Jung, M.
Journal Article
2020l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC are Potent Activators of PPARγ
Gellrich, L.; Heitel, P.; Heering, J.; Kilu, W.; Pollinger, J.; Goebel, T.; Kahnt, A.; Arifi, S.; Pogoda, W.; Paulke, A.; Steinhilber, D.; Proschak, E.; Wurglics, M.; Schubert-Zsilavecz, M.; Chaikuad, A.; Knapp, S.; Bischoff, I.; Fürst, R.; Merk, D.
Journal Article
2020Lack of antiviral activity of darunavir against SARS-CoV-2
Meyer, S. De; Bojkova, D.; Cinatl, J.; Damme, E. Van; Buyck, C.; Loock, M. Van; Woodfall, B.; Ciesek, S.
Journal Article
2020Larvae of the clothing moth tineola bisselliella maintain gut bacteria that secrete enzyme cocktails to facilitate the digestion of keratin
Vilcinskas, A.; Schwabe, M.; Brinkrolf, K.; Plarre, R.; Wielsch, N.; Vogel, H.
Journal Article
2020LC-MS analysis of the degradation products of a sprayable, biodegradable poly(ester-urethane-urea)
Borrowman, C.K.; Bücking, M.; Göckener, B.; Adhikari, R.; Saito, K.; Patti, A.F.
Journal Article
2020Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds
Salado, I.G.; Singh, A.K.; Moreno-Cinos, C.; Sakaine, G.; Siderius, M.; Veken, P. Van Der; Matheeussen, A.; Meer, T. Van Der; Sadek, P.; Gul, S.; Maes, L.; Sterk, G.-J.; Leurs, R.; Brown, D.; Augustyns, K.
Journal Article
2020LEADS-FRAG: A Benchmark Data Set for Assessment of Fragment Docking Performance
Chachulski, L.; Windshügel, B.
Journal Article
2020Lipid Mediator Profiles Predict Response to Therapy with an Oral Frankincense Extract in Relapsing-Remitting Multiple Sclerosis
Stürner, K.H.; Werz, O.; Koeberle, A.; Otto, M.; Pless, O.; Leypoldt, F.; Paul, F.; Heesen, C.
Journal Article
2020The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain
Osthues, T.; Zimmer, B.; Rimola, V.; Klann, K.; Schilling, K.; Mathoor, P.; Angioni, C.; Weigert, A.; Geisslinger, G.; Münch, C.; Scholich, K.; Sisignano, M.
Journal Article
2020Local fixation of antibiotics with fibrin spray on soft tissues: Experimental study on the relevance of the application techniques
Verboket, R.; Marzi, I.; Fleck, S.C.; Frank, J.; Janko, M.
Journal Article
2020Long-term stimulation of toll-like receptor-2 and -4 upregulates 5-LO and 15-LO-2 expression thereby inducing a lipid mediator shift in human monocyte-derived macrophages
Ebert, R.; Cumbana, R.; Lehmann, C.; Kutzner, L.; Toewe, A.; Ferreirós, N.; Parnham, M.J.; Schebb, N.H.; Steinhilber, D.; Kahnt, A.S.
Journal Article
2020Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients
Kreer, C.; Zehner, M.; Weber, T.; Ercanoglu, M.S.; Gieselmann, L.; Rohde, C.; Halwe, S.; Korenkov, M.; Schommers, P.; Vanshylla, K.; Cristanziano, V. Di; Janicki, H.; Brinker, R.; Ashurov, A.; Krähling, V.; Kupke, A.; Cohen-Dvashi, H.; Koch, M.; Eckert, J.M.; Lederer, S.; Pfeifer, N.; Wolf, T.; Vehreschild, M.J.G.T.; Wendtner, C.; Diskin, R.; Gruell, H.; Becker, S.
Journal Article
2020Low brain endocannabinoids associated with persistent non-goal directed nighttime hyperactivity after traumatic brain injury in mice
Vogel, A.; Wilken-Schmitz, A.; Hummel, R.; Lang, M.; Gurke, R.; Schreiber, Y.; Schäfer, M.K.E.; Tegeder, I.
Journal Article
2020Low-Avidity CD4+ T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19
Bacher, P.; Rosati, E.; Esser, D.; Martini, G.R.; Saggau, C.; Schiminsky, E.; Dargvainiene, J.; Schröder, I.; Wieters, I.; Khodamoradi, Y.; Eberhardt, F.; Vehreschild, M.J.G.T.; Neb, H.; Sonntagbauer, M.; Conrad, C.; Tran, F.; Rosenstiel, P.; Markewitz, R.; Wandinger, K.-P.; Augustin, M.; Rybniker, J.; Kochanek, M.; Leypoldt, F.; Cornely, O.A.; Koehler, P.
Journal Article
2020Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
Thurner, L.; Hartmann, S.; Fadle, N.; Regitz, E.; Kemele, M.; Kim, Y.-J.; Bohle, R.M.; Nimmesgern, A.; Müller, L. von; Kempf, V.A.J.; Weniger, M.A.; Neumann, F.; Schneider, N.; Vornanen, M.; Sundström, C.; Leval, L. de; Engert, A.; Eichenauer, D.A.; Küppers, R.; Preuss, K.-D.; Hansmann, M.-L.; Pfreundschuh, M.
Journal Article
2020Lysine acetyltransferase p300/cbp plays an important role in reproduction, embryogenesis and longevity of the pea aphid acyrthosiphon pisum
Kirfel, P.; Vilcinskas, A.; Skaljac, M.
Journal Article
2020Machine-learned association of next-generation sequencing-derived variants in thermosensitive ion channels genes with human thermal pain sensitivity phenotypes
Lötsch, J.; Kringel, D.; Geisslinger, G.; Oertel, B.G.; Resch, E.; Malkusch, S.
Journal Article
2020Machine-learned identification of psychological subgroups with relation to pain interference in patients after breast cancer treatments
Sipilä, R.; Kalso, E.; Lötsch, J.
Journal Article
2020Machine-learning-based knowledge discovery in rheumatoid arthritis-related registry data to identify predictors of persistent pain
Lötsch, J.; Alfredsson, L.; Lampa, J.
Journal Article
2020Machine-learning-derived rules set excludes risk of Parkinson’s disease in patients with olfactory or gustatory symptoms with high accuracy
Lötsch, J.; Haehner, A.; Hummel, T.
Journal Article
2020Macrophage-derived iron-bound lipocalin-2 correlates with renal recovery markers following sepsis-induced kidney damage
Mertens, C.; Kuchler, L.; Sola, A.; Guiteras, R.; Grein, S.; Brüne, B.; Knethen, A. von; Jung, M.
Journal Article
2020The Major Floral Promoter NtFT5 in Tobacco (Nicotiana tabacum) is a Promising Target for Crop Improvement
Schmidt, F.J.; Zimmermann, M.M.; Wiedmann, D.R.; Lichtenauer, S.; Grundmann, L.; Muth, J.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Journal Article
2020Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults
Litou, C.; Psachoulias, D.; Vertzoni, M.; Dressman, J.; Reppas, C.
Journal Article
2020Membrane-based steric exclusion chromatography for the purification of a recombinant baculovirus and its application for cell therapy
Lothert, K.; Sprick, G.; Beyer, F.; Lauria, G.; Czermak, P.; Wolff, M.W.
Journal Article
2020Metabolic Plasticity Is an Essential Requirement of Acquired Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia
Contreras Mostazo, M.G.; Kurrle, N.; Casado, M.; Fuhrmann, D.; Alshamleh, I.; Häupl, B.; Martín-Sanz, P.; Brüne, B.; Serve, H.; Schwalbe, H.; Schnütgen, F.; Marin, S.; Cascante, M.
Journal Article
2020Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer
Salazar, Y.; Zheng, X.; Brunn, D.; Raifer, H.; Picard, F.; Zhang, Y.; Winter, H.; Guenther, S.; Weigert, A.; Weigmann, B.; Dumoutier, L.; Renauld, J.-C.; Waisman, A.; Schmall, A.; Tufman, A.; Fink, L.; Brüne, B.; Bopp, T.; Grimminger, F.; Seeger, W.; Pullamsetti, S.S.; Huber, M.; Savai, R.
Journal Article
2020MicroRNAs as emerging regulators of signaling in the tumor microenvironment
Syed, S.N.; Brüne, B.
Journal Article
2020MicroRNAs regulate innate immunity against uropathogenic and commensal-like Escherichia coli infections in the surrogate insect model Galleria mellonella
Mukherjee, K.; Amsel, D.; Kalsy, M.; Billion, A.; Dobrindt, U.; Vilcinskas, A.
Journal Article
2020MiT/TFE factors control ER‐phagy via transcriptional regulation of FAM134B
Cinque, L.; Leonibus, C. De.; Iavazzo, M.; Krahmer, N.; Intartaglia, D.; Salierno, F.G.; Cegli, R. De; Malta, C. Di; Svelto, M.; Lanzara, C.; Maddaluno, M.; Wanderlingh, L.G.; Huebner, A.K.; Cesana, M.; Bonn, F.; Polishchuk, E.; Hübner, C.A.; Conte, I.; Dikic, I.; Mann, M.; Ballabio, A.; Sacco, F.; Grumati, P.; Settembre, C.
Journal Article
2020Molecular farming - the slope of enlightenment
Fischer, R.; Buyel, J.F.
Journal Article
2020Molecular Networking-Guided Discovery and Characterization of Stechlisins, a Group of Cyclic Lipopeptides from a Pseudomonas sp.
Marner, M.; Patras, M.A.; Kurz, M.; Zubeil, F.; Förster, F.; Schuler, S.; Bauer, A.; Hammann, P.; Vilcinskas, A.; Schaberle, T.F.; Glaeser, J.
Journal Article
2020Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020
Muenchhoff, M.; Mairhofer, H.; Nitschko, H.; Grzimek-Koschewa, N.; Hoffmann, D.; Berger, A.; Rabenau, H.; Widera, M.; Ackermann, N.; Konrad, R.; Zange, S.; Graf, A.; Krebs, S.; Blum, H.; Sing, A.; Liebl, B.; Wölfel, R.; Ciesek, S.; Drosten, C.; Protzer, U.; Boehm, S.; Keppler, O.T.
Journal Article
2020Natural antiviral compound silvestrol modulates human monocyte-derived macrophages and dendritic cells
Blum, L.; Geisslinger, G.; Parnham, M.J.; Grünweller, A.; Schiffmann, S.
Journal Article
2020Neuropathic and cAMP-induced pain behavior is ameliorated in mice lacking CNGB1
Kallenborn-Gerhardt, W.; Metzner, K.; Lu, R.; Petersen, J.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Nemirovski, D.; Del Turco, D.; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A.
Journal Article
2020A new citrinin derivative from the Indonesian Marine Sponge-Associated Fungus Penicillium citrinum
Sabdaningsih, A.; Liu, Y.; Mettal, U.; Heep, J.; Riyanti; Wang, L.; Cristianawati, O.; Nuryadi, H.; Sibero, M.T.; Marner, M.; Radjasa, O.K.; Sabdono, A.; Trianto, A.; Schäberle, T.F.
Journal Article
2020Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease
Schultheiß, C.; Paschold, L.; Simnica, D.; Mohme, M.; Willscher, E.; Wenserski, L. von; Scholz, R.; Wieters, I.; Dahlke, C.; Tolosa, E.; Sedding, D.G.; Ciesek, S.; Addo, M.; Binder, M.
Journal Article
2020A non-parametric effect-size measure capturing changes in central tendency and data distribution shape
Lötsch, J.; Ultsch, A.
Journal Article
2020The NORMAN Association and the European Partnership for Chemicals Risk Assessment (PARC): Let’s cooperate!
Dulio, V.; Koschorreck, J.; Bavel, B. van; Brink, P. van den; Hollender, J.; Munthe, J.; Schlabach, M.; Aalizadeh, R.; Agerstrand, M.; Ahrens, L.; Allan, I.; Alygizakis, N.; Barcelo, D.; Bohlin-Nizzetto, P.; Boutroup, S.; Brack, W.; Bressy, A.; Christensen, J.H.; Cirka, L.; Covaci, A.; Derksen, A.; Deviller, G.; Dingemans, M.M.L.; Engwall, M.; Fatta-Kassinos, D.; Gago-Ferrero, P.; Hernández, F.; Herzke, D.; Hilscherová, K.; Hollert, H.; Junghans, M.; Kasprzyk-Hordern, B.; Keiter, S.; Kools, S.A.E.; Kruve, A.; Lambropoulou, D.; Lamoree, M.; Leonards, P.; Lopez, B.; López de Alda, M.; Lundy, L.; Makovinská, J.; Marigómez, I.; Martin, J.W.; McHugh, B.; Miège, C.; O’Toole, S.; Perkola, N.; Polesello, S.; Posthuma, L.; Rodriguez-Mozaz, S.; Roessink, I.; Rostkowski, P.; Ruedel, H.; Samanipour, S.; Schulze, T.; Schymanski, E.L.; Sengl, M.; Tarábek, P.; Ten Hulscher, D.; Thomaidis, N.; Togola, A.; Valsecchi, S.; Leeuwen, S. van; Ohe, P. von der; Vorkamp, K.; Vrana, B.; Slobodnik, J.
Journal Article
2020Novel Biomarkers for Change in Renal Function in People With Dysglycemia
Gerstein, H.C.; Paré, G.; McQueen, M.J.; Lee, S.F.; Bangdiwala, S.I.; Kannt, A.; Hess, S.
Journal Article
2020Novel multiple swab method enables high efficiency in SARS‐CoV‐2 screenings without loss of sensitivity for screening of a complete population
Schmidt, M.; Hoehl, S.; Berger, A.; Zeichhardt, H.; Hourfar, K.; Ciesek, S.; Seifried, E.
Journal Article
2020Nrf2 - A Molecular Target for Sepsis Patients in Critical Care
Gunne, S.; Heinicke, U.; Parnham, M.J.; Laux, V.; Zacharowski, K.; Knethen, A.V.
Journal Article
2020The omega-3 lipid 17,18-EEQ sensitizes TRPV1 and TRPA1 in sensory neurons through the prostacyclin receptor (IP)
Schäfer, S.M.G.; Sendetski, M.; Angioni, C.; Nüsing, R.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Journal Article
2020Opportunities to debottleneck the downstream processing of the oncolytic measles virus
Loewe, D.; Dieken, H.; Grein, T.A.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2020Optimized qRT-PCR Approach for the Detection of Intra- and Extra-Cellular SARS-CoV-2 RNAs
Toptan, T.; Hoehl, S.; Westhaus, S.; Bojkova, D.; Berger, A.; Rotter, B.; Hoffmeier, K.; Cinatl, J.; Ciesek, S.; Widera, M.
Journal Article
2020Optimizing product quality in molecular farming
Schiermeyer, Andreas
Journal Article
2020The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs
Willems, S.; Kilu, W.; Ni, X.; Chaikuad, A.; Knapp, S.; Heering, J.; Merk, D.
Journal Article
2020Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19)
Puntmann, V.O.; Carerj, M.L.; Wieters, I.; Fahim, M.; Arendt, C.; Hoffmann, J.; Shchendrygina, A.; Escher, F.; Vasa-Nicotera, M.; Zeiher, A.M.; Vehreschild, M.; Nagel, E.
Journal Article
2020Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
Shin, D.; Mukherjee, R.; Grewe, D.; Bojkova, D.; Baek, K.; Bhattacharya, A.; Schulz, L.; Widera, M.; Mehdipour, A.R.; Tascher, G.; Geurink, P.P.; Wilhelm, A.; Heden van Noort, G.J. van der; Ovaa, H.; Müller, S.; Knobeloch, K.-P.; Rajalingam, K.; Schulman, B.A.; Cinatl, J.; Hummer, G.; Ciesek, S.; Dikic, I.
Journal Article
2020Parallel evolution of complex centipede venoms
Jenner, R.; Reumont, B. von; Campbell, L.; Undheim, E.
Journal Article
2020Per- and polyfluoroalkyl substances in the German environment
Kotthoff, M.; Fliedner, A.; Rüdel, H.; Göckener, B.; Bücking, M.; Biegel-Engler, A.; Koschorreck, J.
Journal Article
2020Persistent, mobile and toxic substances in the environment: A spotlight on current research and regulatory activities
Rüdel, Heinz; Körner, Wolfgang; Letzel, Thomas; Neumann, Michael; Nödler, Karsten; Reemtsma, Thorsten
Journal Article
2020Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ)
Hinnah, K.; Willems, S.; Morstein, J.; Heering, J.; Hartrampf, F.W.W.; Broichhagen, J.; Leippe, P.; Merk, D.; Trauner, D.
Journal Article
2020Phylotranscriptomic evidence for pervasive ancient hybridization among Old World salamanders
Rancilhac, L.; Irisarri, I.; Angelini, C.; Arntzen, J.W.; Babik, W.; Bossuyt, F.; Künzel, S.; Lüddecke, T.; Pasmans, F.; Sanchez, E.; Weisrock, D.; Veith, M.; Wielstra, B.; Steinfartz, S.; Hofreiter, M.; Philippe, H.; Vences, M.
Journal Article
2020Physiologically based pharmacokinetic model outputs depend on dissolution data and their input
Klumpp, L.; Dressman, J.
Journal Article
2020Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Predict the Impact of CYP2C9 Genetic Polymorphisms, Co-Medication and Formulation on the Pharmacokinetics and Pharmacodynamics of Flurbiprofen
Loisios-Konstantinidis, I.; Cristofoletti, R.; Jamei, M.; Turner, D.; Dressman, J.
Journal Article
2020A physiologically-based nanocarrier biopharmaceutics model to reverse-engineer the in vivo drug release
Nagpal, S.; Braner, S.; Modh, H.; Tan, A.X.X.; Mast, M.-P.; Chichakly, K.; Albrecht, V.; Wacker, M.G.
Journal Article
2020Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX
Visser, M.; Oerle, R. van; Ten Cate, H.; Laux, V.; Mackman, N.; Heitmeier, S.; Spronk, H.M.H.
Journal Article
2020Potential Applications of Plant Biotechnology against SARS-CoV-2
Capell, T.; Twyman, R.M.; Armario-Najera, V.; Ma, J.K.-C.; Schillberg, S.; Christou, P.
Journal Article
2020Predicting human pharmacokinetics of liposomal temoporfin using a hybrid in silico model
Jablonka, L.; Ashtikar, M.; Gao, G.F.; Thurn, M.; Modh, H.; Wang, J.-W.; Preuß, A.; Scheglmann, D.; Albrecht, V.; Röder, B.; Wacker, M.G.
Journal Article
2020Prediction of advanced fibrosis in non-alcoholic fatty liver disease using gut microbiota-based approaches compared with simple non-invasive tools
Lang, S.; Farowski, F.; Martin, A.; Wisplinghoff, H.; Vehreschild, M.J.G.T.; Krawczyk, M.; Nowag, A.; Kretzschmar, A.; Scholz, C.; Kasper, P.; Roderburg, C.; Lammert, F.; Goeser, T.; Steffen, H.-M.; Demir, M.
Journal Article
2020Prevalence of third-generation cephalosporin-resistant Enterobacterales colonization on hospital admission and ESBL genotype-specific risk factors: a cross-sectional study in six German university hospitals
Rohde, A.M.; Zweigner, J.; Wiese-Posselt, M.; Schwab, F.; Behnke, M.; Kola, A.; Schröder, W.; Peter, S.; Tacconelli, E.; Wille, T.; Feihl, S.; Querbach, C.; Gebhardt, F.; Gölz, H.; Schneider, C.; Mischnik, A.; Vehreschild, M.J.G.T.; Seifert, H.; Kern, W.V.; Gastmeier, P.; Hamprecht, A.
Journal Article
2020Production and purification of fructo-oligosaccharides using an enzyme membrane bioreactor and subsequent fermentation with probiotic Bacillus coagulans
Fan, R.; Burghardt, J.P.; Prell, F.; Zorn, H.; Czermak, P.
Journal Article
2020The production of isoprene from cellulose using recombinant Clostridium cellulolyticum strains expressing isoprene synthase
Janke, C.; Gaida, S.; Jennewein, S.
Journal Article
2020Progranulin deficiency confers resistance to autoimmune encephalomyelitis in mice
Schmitz, K.; Wilken-Schmitz, A.; Vasic, V.; Brunkhorst, R.; Schmidt, M.; Tegeder, I.
Journal Article
2020Proline-Rich Antimicrobial Peptides in Medicinal Maggots of Lucilia sericata Interact with Bacterial DnaK but do not Inhibit Protein Synthesis
Cytrynska, M.; Rahnamaeian, M.; Zdybicka-Barabas, A.; Dobslaff, K.; Züchner, T.; Sacheau, G.; Innis, C.A.; Vilcinskas, A.
Journal Article
2020Protective effect of Soluble Epoxide Hydrolase Inhibition in Retinal Vasculopathy associated with Polycystic Kidney Disease
Lin, J.; Hu, J.; Schlotterer, A.; Wang, J.; Kolibabka, M.; Awwad, K.; Dietrich, N.; Breitschopf, K.; Wohlfart, P.; Kannt, A.; Lorenz, K.; Feng, Y.; Popp, R.; Hoffmann, S.; Fleming, I.; Hammes, H.P.
Journal Article
2020Proteo-Transcriptomic Analysis Identifies Potential Novel Toxins Secreted by the Predatory, Prey-Piercing Ribbon Worm Amphiporus lactifloreus
Reumont, B.M. von; Lüddecke, T.; Timm, T.; Lochnit, G.; Vilcinskas, A.; Döhren, J. von; Nilsson, M.A.
Journal Article
2020Proteomics as an alternative approach for hazard characterization and the identification of specific chemical targets: Elucidation of potential biomarkers for differentiating endocrine disruption from hepatotoxicity
Ayobahan, Steve Uwa
: Hollert, Henner; Schäfers, Christoph; Schäffer, Andreas
Dissertation
2020Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
Bojkova, D.; Klann, K.; Koch, B.; Widera, M.; Krause, D.; Ciesek, S.; Cinatl, J.; Münch, C.
Journal Article
2020Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells
Emmerich, A.C.; Wellstein, J.; Ossipova, E.; Baumann, I.; Lengqvist, J.; Kultima, K.; Jakobsson, P.-J.; Steinhilber, D.; Saul, M.J.
Journal Article
2020Quality of life of patients with head and neck cancer after prophylactic percutaneous-gastrostomy
Hausmann, J.; Kubesch, A.; Goettlich, C.M.; Rey, J.; Wächtershäuser, A.; Bojunga, J.; Blumenstein, I.
Journal Article
2020Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. rigida Esper
Jiso, A.; Kittiwisut, S.; Chantakul, R.; Yuenyongsawad, S.; Putchakarn, S.; Schäberle, T.F.; Temkitthaworn, P.; Ingkaninan, K.; Chaithirayanon, K.; Plubrukarn, A.
Journal Article
2020Rab27a Contributes to the Processing of Inflammatory Pain in Mice
Gross, T.; Wack, G.; Syhr, K.M.J.; Tolmachova, T.; Seabra, M.C.; Geisslinger, G.; Niederberger, E.; Schmidtko, A.; Kallenborn-Gerhardt, W.
Journal Article
2020The Radiokitchen: Understanding chemical reactions during food processing
Bücking, Mark; Göckener, Bernd
Journal Article
2020Random forests followed by computed ABC analysis as a feature selection method for machine learning in biomedical data
Lötsch, J.; Ultsch, A.
Conference Paper
2020A Randomized Open label Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease (RECOVER): A structured summary of a study protocol for a randomised controlled trial
Janssen, M.; Schäkel, U.; Djuka Fokou, C.; Krisam, J.; Stermann, J.; Kriegsmann, K.; Haberbosch, I.; Novotny, J.P.; Weber, S.; Vehreschild, M.; Bornhäuser, M.; Bullinger, L.; Schmitt, M.; Liebregts, T.; Dreger, P.; Lorenz, H.-M.; Plaszczyca, A.; Bartenschlager, R.; Müller, B.; Kräusslich, H.-G.; Halama, N.; Jäger, D.; Schlenk, R.F.; Leo, A.; Meuer, S.; Weigand, M.A.; Motsch, J.; Merle, U.; Denkinger, C.M.; Müller-Tidow, C.
Journal Article
2020Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis
Frey, S.; Sticht, H.; Wilsmann-Theis, D.; Gerschütz, A.; Wolf, K.; Löhr, S.; Haskamp, S.; Frey, B.; Hahn, M.; Ekici, A.B.; Uebe, S.; Thiel, C.; Reis, A.; Burkhardt, H.; Behrens, F.; Köhm, M.; Rech, J.; Schett, G.; Assmann, G.; Kingo, K.; Koks, S.; Mössner, R.; Prinz, J.C.; Oji, V.; Schulz, P.; Muñoz, L.E.; Kremer, A.E.; Wenzel, J.; Hüffmeier, U.
Journal Article
2020Real-world data about emotional stress, disability and need for social care in a German IBD patient cohort
Kubesch, A.; Boulahrout, P.; Filmann, N.; Blumenstein, I.; Hausmann, J.
Journal Article
2020Recent advances in Salamandra skin poison research
Lüddecke, T.
Journal Article
2020Redox Regulation of PPARγ in Polarized Macrophages
Trümper, V.; Wittig, I.; Heidler, J.; Richter, F.; Brüne, B.; Knethen, A. von
Journal Article
2020Reduced association between dendritic cells and corneal sub‐basal nerve fibers in patients with fibromyalgia syndrome
Klitsch, A.; Evdokimov, D.; Frank, J.; Thomas, D.; Saffer, N.; Altenschildesche, C. Meyer zu; Sisignano, M.; Kampik, D.; Malik, R.A.; Sommer, C.; Üçeyler, N.
Journal Article
2020Relevance of instruments for measurements of quality of life in the AMNOG context
Schneider, N.
Book Article
2020Removal of Small-Molecular Byproducts from Crude Fructo-Oligosaccharide Preparations by Fermentation Using the Endospore-Forming Probiotic Bacillus coagulans
Fan, R.; Burghardt, J.P.; Xiong, T.; Czermak, P.
Journal Article
2020Reprograming of epigenetic mechanisms controlling host insect immunity and development in response to egg-laying by a parasitoid wasp
Özbek, R.; Mukherjee, K.; Uçkan, F.; Vilcinskas, A.
Journal Article
2020Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer
Sarode, P.; Zheng, X.; Giotopoulou, G.A.; Weigert, A.; Kuenne, C.; Günther, S.; Friedrich, A.; Gattenlöhner, S.; Stiewe, T.; Brüne, B.; Grimminger, F.; Stathopoulos, G.T.; Pullamsetti, S.S.; Seeger, W.; Savai, R.
Journal Article
2020Retraction notice to "Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells" [Stem Cell Res. 31 (2018) 62-70]
Trillhaase, A.; Haferkamp, U.; Rangnau, A.; Märtens, M.; Schmidt, B.; Trilck, M.; Seibler, P.; Aherrahrou, R.; Erdmann, J.; Aherrahrou, Z.
Journal Article
2020Retrospective analysis of cyclic volatile methylsiloxanes in archived German fish samples covering a period of two decades
Radermacher, Georg; Rüdel, Heinz; Wesch, Charlotte; Böhnhardt, Anna; Koschorreck, Jan
Journal Article
2020Reversible Small Molecule Inhibitors of MAO A and MAO B with Anilide Motifs
Hagenow, J.; Hagenow, S.; Grau, K.; Khanfar, M.; Hefke, L.; Proschak, E.; Stark, H.
Journal Article
2020Robot Cookies - Plant Cell Packs as an Automated High-Throughput Screening Platform Based on Transient Expression
Gengenbach, B.B.; Opdensteinen, P.; Buyel, J.F.
Journal Article
2020Robustheitsuntersuchung zur Resorptionsverfügbarkeit von Schadstoffen in Böden. Abschlussbericht
Barkowski, Dietmar; Krüger, Gerald; Machtolf, Monika; Derz, Kerstin; Küchler, Frank
Report
2020S1P d20:1, an endogenous modulator of S1P d18:1/S1P2-dependent signaling
Vutukuri, R.; Koch, A.; Trautmann, S.; Schreiber, Y.; Thomas, D.; Mayser, F.; Meyer zu Heringdorf, D.; Pfeilschifter, J.; Pfeilschifter, W.; Brunkhorst, R.
Journal Article
2020S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion
Olesch, C.; Sirait-Fischer, E.; Berkefeld, M.; Fink, A.F.; Susen, R.M.; Ritter, B.; Michels, B.E.; Steinhilber, D.; Greten, F.R.; Savai, R.; Takeda, K.; Brüne, B.; Weigert, A.
Journal Article
2020S1PR4-dependent CCL2 production promotes macrophage recruitment in a murine psoriasis model
Schuster, C.; Huard, A.; Sirait-Fischer, E.; Dillmann, C.; Brüne, B.; Weigert, A.
Journal Article
2020SARS-CoV-2/COVID-19: Systematischer Review zu Anforderungen an die persönliche Schutzausrüstung bei primärem Patientenkontakt und Strukturierung des Operationsbereiches
Schnitzbauer, A.A.; Kempf, V.A.J.; Hack, D.; Ciesek, S.; Meier, S.; Vehreschild, M.J.G.T.; Wicker, S.; Kippke, U.; Graf, J.; Marzi, I.
Journal Article
2020SARS‐CoV‐2 asymptomatic and symptomatic patients and risk for transfusion transmission
Corman, V.M.; Rabenau, H.F.; Adams, O.; Oberle, D.; Funk, M.B.; Keller-Stanislawski, B.; Timm, J.; Drosten, C.; Ciesek, S
Journal Article
2020Saturation mutagenesis to improve the degradation of azo dyes by versatile peroxidase and application in form of VP-coated yeast cell walls
Ilić Đurđić, K.; Ostafe, R.; Đurđević Đelmaš, A.; Popović, N.; Schillberg, S.; Fischer, R.; Prodanovic, R.
Journal Article
2020A scalable downstream process for the purification of the cell culture-derived Orf virus for human or veterinary applications
Lothert, K.; Pagallies, F.; Eilts, F.; Sivanesapillai, A.; Hardt, M.; Moebus, A.; Feger, T.; Amann, R.; Wolff, M.W.
Journal Article
2020Schmerzmodelle und klinische Schmerzforschung sind kein Widerspruch
Lötsch, J.; Geisslinger, G.; Walter, C.
Journal Article
2020Schulung von Medizinischen Fachangestellten bei hausärztlichen Forschungsprojekten. Wissensgewinn und Unterschiede zwischen einer Präsenzschulung und dem Selbststudium eines Schulungshandbuches
Mergenthal, K.; Schulz-Rothe, S.; Siebenhofer, A.; Gerlach, F.M.; Rossmanith, T.; Petersen, J.J.
Journal Article
2020Seasonal phenotype-specific expression of microRNAs during metamorphosis in the European map butterfly Araschnia levana
Mukherjee, K.; Baudach, A.; Vogel, H.; Vilcinskas, A.
Journal Article
2020Seasonal variability in metal and metalloid burdens of mussels: Using data from the German Environmental Specimen Bank to evaluate implications for long-term mussel monitoring programs
Knopf, Burkhard; Fliedner, Annette; Radermacher, Georg; Rüdel, Heinz; Paulus, Martin; Pirntke, Ulrike; Koschorreck, Jan
Journal Article
2020Secukinumab versus adalimumab for treatment of active psoriatic arthritis (EXCEED): A double-blind, parallel-group, randomised, active-controlled, phase 3b trial
McInnes, I.B.; Behrens, F.; Mease, P.J.; Kavanaugh, A.; Ritchlin, C.; Nash, P.; Masmitja, J.G.; Goupille, P.; Korotaeva, T.; Gottlieb, A.B.; Martin, R.; Ding, K.; Pellet, P.; Mpofu, S.; Pricop, L.
Journal Article
2020Selection and application of trophic magnification factors for priority substances to normalize freshwater fish monitoring data under the European Water Framework Directive: A case study
Rüdel, Heinz; Kosfeld, Verena; Fliedner, Annette; Radermacher, Georg; Schlechtriem, Christian; Duffek, Anja; Rauert, Caren; Koschorreck, Jan
Journal Article
2020Selection of chromatographic methods for the purification of cell culture-derived Orf virus for its application as a vaccine or viral vector
Lothert, K.; Pagallies, F.; Feger, T.; Amann, R.; Wolff, M.W.
Journal Article
2020A Selective Modulator of Peroxisome Proliferator-Activated Receptor γ with an Unprecedented Binding Mode
Hanke, T.; Cheung, S.-Y.; Kilu, W.; Heering, J.; Ni, X.; Planz, V.; Schierle, S.; Faudone, G.; Friedrich, M.; Wanior, M.; Werz, O.; Windbergs, M.; Proschak, E.; Schubert-Zsilavecz, M.; Chaikuad, A.; Knapp, S.; Merk, D.
Journal Article
2020Sensitive aflatoxin B1 detection using nanoparticle-based competitive magnetic immunodetection
Pietschmann, J.; Spiegel, H.; Krause, H.-J.; Schillberg, S.; Schröper, F.
Journal Article
2020A sensitive in vitro performance assay reveals the in vivo drug release mechanisms of long-acting medroxyprogesterone acetate microparticles
Gao, G.F.; Thurn, M.; Wendt, B.; Parnham, M.J.; Wacker, M.G.
Journal Article
2020Short-term variability of the human serum metabolome depending on nutritional and metabolic health status
Agueusop, I.; Musholt, P.B.; Klaus, B.; Hightower, K.; Kannt, A.
Journal Article
2020Significant weight loss in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database
Hughes, M.; Heal, C.; Siegert, E.; Hachulla, E.; Airó, P.; Riccardi, A.; Distler, O.; Matucci-Cerinic, M.; Köhm, M. et al.
Journal Article
2020Silencing of the DNA methyltransferase 1 associated protein 1 (DMAP1) gene in the invasive ladybird Harmonia axyridis implies a role of the DNA methyltransferase 1-DMAP1 complex in female fecundity
Gegner, J.; Gegner, T.; Vogel, H.; Vilcinskas, A.
Journal Article
2020Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells
Karathanasis, C.; Medler, J.; Fricke, F.; Smith, S.; Malkusch, S.; Widera, D.; Fulda, S.; Wajant, H.; Wijk, S.J.L. van; Dikic, I.; Heilemann, M.
Journal Article
2020Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological Processes
Bojkova, D.; Westhaus, S.; Costa, R.; Timmer, L.; Funkenberg, N.; Korencak, M.; Streeck, H.; Vondran, F.; Broering, R.; Heinrichs, S.; Lang, K.S.; Ciesek, S.
Journal Article
2020Soluble epoxide hydrolase inhibitors with carboranes as non-natural 3-D pharmacophores
Scholz, M.S.; Wingen, L.M.; Brunst, S.; Wittmann, S.K.; Cardoso, I.L.A.; Weizel, L.; Proschak, E.
Journal Article
2020The Specific IKKε/TBK1 Inhibitor Amlexanox Suppresses Human Melanoma by the Inhibition of Autophagy, NF-κB and MAP Kinase Pathways
Möller, M.; Wasel, J.; Schmetzer, J.; Weiß, U.; Meissner, M.; Schiffmann, S.; Weigert, A.; Möser, C.V.; Niederberger, E.
Journal Article
2020Sphingosine kinases are involved in macrophage NLRP3 inflammasome transcriptional induction
Syed, S.N.; Weigert, A.; Brüne, B.
Journal Article
2020Suitability of the z-Factor for Dissolution Simulation of Solid Oral Dosage Forms
Hofsäss, M.A.; Dressman, J.
Journal Article
2020Supplementation of sulfur-containing amino acids or essential amino acids does not reverse the hepatic lipid-lowering effect of a protein-rich insect meal in obese zucker rats
Meyer, S.; Schäfer, L.; Röhrig, J.; Maheshwari, G.; Most, E.; Zorn, H.; Ringseis, R.; Eder, K.; Gessner, D.K.
Journal Article
2020Sustained improvement in work outcomes in employed patients with rheumatoid arthritis during 2 years of adalimumab therapy: An observational cohort study
Behrens, F.; Tony, H.-P.; Koehm, M.; Schwaneck, E.C.; Gnann, H.; Greger, G.; Burkhardt, H.; Schmalzing, M.
Journal Article
2020Systematic Assessment of Fragment Identification for Multitarget Drug Design
Brunst, S.; Kramer, J.S.; Kilu, W.; Heering, J.; Pollinger, J.; Hiesinger, K.; George, S.; Steinhilber, D.; Merk, D.; Proschak, E.
Journal Article
2020A systematic comparison of chloroplast genome assembly tools
Freudenthal, J.A.; Pfaff, S.; Terhoeven, N.; Korte, A.; Ankenbrand, M.J.; Förster, F.
Journal Article
2020Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling
Wigington, C.P.; Roy, J.; Damle, N.P.; Yadav, V.K.; Blikstad, C.; Resch, E.; Wong, C.J.; Mackay, D.R.; Wang, J.T.; Krystkowiak, I.; Bradburn, D.A.; Tsekitsidou, E.; Hong, S.H.; Kaderali, M.A.; Xu, S.-L.; Stearns, T.; Gingras, A.-C.; Ullman, K.S.; Ivarsson, Y.; Davey, N.E.; Cyert, M.S.
Journal Article
2020Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia
Zhao, X.-Y.; Wilmen, A.; Wang, D.; Wang, X.; Bauzon, M.; Kim, J.-Y.; Linden, L.; Li, L.; Egner, U.; Marquardt, T.; Moosmayer, D.; Tebbe, J.; Glück, J.M.; Ellinger, P.; McLean, K.; Yuan, S.; Yegneswaran, S.; Jiang, X.; Evans, V.; Gu, J.-M.; Schneider, D.; Zhu, Y.; Xu, Y.; Mallari, C.; Hesslein, A.; Wang, Y.; Schmidt, N.; Gutberlet, K.; Ruehl-Fehlert, C.; Freyberger, A.
Journal Article
2020Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis
Waidmann, O.; Pleli, T.; Weigert, A.; Imelmann, E.; Kakoschky, B.; Schmithals, C.; Döring, C.; Frank, M.; Longerich, T.; Köberle, V.; Hansmann, M.-L.; Brüne, B.; Zeuzem, S.; Piiper, A.; Dikic, I.
Journal Article
2020Tenebrio molitor larvae meal affects the cecal microbiota of growing pigs
Meyer, S.; Gessner, D.K.; Maheshwari, G.; Röhrig, J.; Friedhoff, T.; Most, E.; Zorn, H.; Ringseis, R.; Eder, K.
Journal Article
2020Terpenoids from the Coral-Derived Fungus Trichoderma harzianum (XS-20090075) Induced by Chemical Epigenetic Manipulation
Shi, T.; Shao, C.-L.; Liu, Y.; Zhao, D.-L.; Cao, F.; Fu, X.-M.; Yu, J.-Y.; Wu, J.-S.; Zhang, Z.-K.; Wang, C.-Y.
Journal Article
2020Testing the bioaccumulation of manufactured nanomaterials in the freshwater bivalve Corbicula fluminea using a new test method
Kühr, Sebastian; Meisterjahn, Boris; Schröder, Nicola; Knopf, Burkhard; Völker, Doris; Schwirn, Kathrin; Schlechtriem, Christian
Journal Article
2020Therapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Journal Article
2020Therapiestrategien der Psoriasisarthritis
Köhm, M.; Burkhardt, H.; Behrens, F.
Journal Article
2020Thirty years of CMV seroprevalence - a longitudinal analysis in a German university hospital
Hoehl, S.; Berger, A.; Ciesek, S.; Rabenau, H.F.
Journal Article
2020A tiered high-throughput screening approach for evaluation of estrogen and androgen receptor modulation by environmentally relevant bisphenol A substitutes
Keminer, Oliver; Teigeler, Matthias; Kohler, Manfred; Wenzel, Andrea; Arning, Jürgen; Kaßner, Franziska; Windshügel, Björn; Eilebrecht, Elke
Journal Article
2020TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
Bestle, D.; Heindl, M.R.; Limburg, H.; Van Lam van, T.; Pilgram, O.; Moulton, H.; Stein, D.A.; Hardes, K.; Eickmann, M.; Dolnik, O.; Rohde, C.; Klenk, H.-D.; Garten, W.; Steinmetzer, T.; Böttcher-Friebertshäuser, E.
Journal Article
2020Total Synthesis and Structure Revision of (−)-Avicennone C
Kleiner, Y.; Hammann, P.; Becker, J.; Bauer, A.; Pöverlein, C.; Schuler, S.M.M.
Journal Article
2020Tracing neglected venom systems: Prediction of the industrial potential by a multi-disciplinary data network
Kirchhoff, K.N.; Vilcinskas, A.; Wilke, T.
Journal Article
2020Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Pt.1: Analytical Results Including a Modified Total Oxidizable Precursor Assay
Göckener, Bernd; Eichhorn, Maria; Lämmer, René; Kotthoff, Matthias; Kowalczyk, Janine; Numata, Jorge; Schafft, Helmut; Lahrssen-Wiederholt, Monika; Bücking, Mark
Journal Article
2020Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Pt.2: Toxicokinetic Results Including the Role of Precursors
Kowalczyk, Janine; Göckener, Bernd; Eichhorn, Maria; Kotthoff, Matthias; Bücking, Mark; Schafft, Helmut; Lahrssen-Wiederholt, Monika; Numata, Jorge
Journal Article
2020Translation of TNFAIP2 is tightly controlled by upstream open reading frames
Scholz, A.; Rappl, P.; Böffinger, N.; Mota, A.C.; Brüne, B.; Schmid, T.
Journal Article
2020Translational tarantula phylogenomics: Evolution of theraphosid spiders and their defensive arsenal with implications for venom bioprospecting
Lüddecke, T.
Journal Article
2020Treatment of invasive fungal diseases in cancer patients—Revised 2019 Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
Ruhnke, M.; Cornely, O.A.; Schmidt-Hieber, M.; Alakel, N.; Boell, B.; Buchheidt, D.; Christopeit, M.; Hasenkamp, J.; Heinz, W.J.; Hentrich, M.; Karthaus, M.; Koldehoff, M.; Maschmeyer, G.; Panse, J.; Penack, O.; Schleicher, J.; Teschner, D.; Ullmann, A.J.; Vehreschild, M.; Lilienfeld-Toal, M. von; Weissinger, F.; Schwartz, S.
Journal Article
2020Treatment‐to‐Target With Apremilast in Psoriatic Arthritis: The Probability of Achieving Targets and Comprehensive Control of Disease Manifestations
Mease, P.J.; Gladman, D.D.; Ogdie, A.; Coates, L.C.; Behrens, F.; Kavanaugh, A.; McInnes, I.; Queiro, R.; Guerette, B; Brunori, M.; Teng, L.; Smolen, J.S.
Journal Article
2020Tumors provoke inflammation and perineural microlesions at adjacent peripheral nerves
Cohnen, Jennifer; Kornstädt, Lisa; Hahnefeld, Lisa; Ferreiros, Nerea; Pierre, Sandra; Koehl, Ulrike; Deller, Thomas; Geisslinger, Gerd; Scholich, Klaus
Journal Article
2020Turbidimetry and dielectric spectroscopy as process analytical technologies for mammalian and insect cell cultures
Käßer, L.; Zitzmann, J.; Grein, T.; Weidner, T.; Salzig, D.; Czermak, P.
Book Article
2020UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells
Schömel, N.; Gruber, L.; Alexopoulos, S.J.; Trautmann, S.; Olzomer, E.M.; Byrne, F.L.; Hoehn, K.L.; Gurke, R.; Thomas, D.; Ferreiros, N.; Geisslinger, G.; Wegner, M.-S.
Journal Article
2020Die Umweltprobenbank des Bundes - Umwelt- und Humanproben
Weber, T.; Koschorrek, J.; Rüther, M.; Körner, A.; Knopf, B.; Kotthoff, M.; Rüdel, H.; Lermen, D.; Bartel-Steinbach, M.; Göen, T.; Paulus, M.; Klein, R.; Veith, M.; Kolossa-Gehring, M.
Journal Article
2020Unraveling the Pharmacological Potential of Lichen Extracts in the Context of Cancer and Inflammation With a Broad Screening Approach
Ingelfinger, R.; Henke, M.; Roser, L.; Ulshöfer, T.; Calchera, A.; Singh, G.; Parnham, M.J.; Geisslinger, G.; Fürst, R.; Schmitt, I.; Schiffmann, S.
Journal Article
2020Unravelling the uptake pathway and accumulation of silver from manufactured silver nanoparticles in the freshwater amphipod Hyalella azteca using correlative microscopy
Kühr, Sebastian; Klehm, Jessica; Stehr, Claudia; Menzel, Matthias; Schlechtriem, Christian
Journal Article
2020Untersuchungen zur möglichen Freisetzung von Nanopartikeln bei der Ablagerung und bodenbezogenen Anwendung von mineralischen Abfällen. Abschlussbericht
Oischinger, Jürgen; Meiller, Martin; Daschner, Robert; Hennecke, Dieter; Hund-Rinke, Kerstin; Meisterjahn, Boris; Schröder, Nicola
Report
2020Use of carbapenems and glycopeptides increases risk for Clostridioides difficile infections in acute myeloid leukemia patients undergoing intensive induction chemotherapy
Ballo, O.; Kreisel, E.-M.; Eladly, F.; Brunnberg, U.; Stratmann, J.; Hunyady, P.; Hogardt, M.; Wichelhaus, T.A.; Kempf, V.A.J.; Steffen, B.; Vehreschild, J.J.; Vehreschild, M.J.G.T.; Finkelmeier, F.; Serve, H.; Brandts, C.H.
Journal Article
2020The use of PBPK/PD to establish clinically relevant dissolution specifications for zolpidem immediate release tablets
Paraiso, R.L.M.; Rose, R.H.; Fotaki, N.; McAllister, M.; Dressman, J.B.
Journal Article
2020Vancomycin-resistant Enterococcus faecium colonizing patients on hospital admission in Germany: Prevalence and molecular epidemiology
Xanthopoulou, K.; Peter, S.; Tobys, D.; Behnke, M.; Dinkelacker, A.G.; Eisenbeis, S.; Falgenhauer, J.; Falgenhauer, L.; Fritzenwanker, M.; Gölz, H.; Häcker, G.; Higgins, P.G.; Imirzalioglu, C.; Käding, N.; Kern, W.V.; Kramme, E.; Kola, A.; Mischnik, A.; Rieg, S.; Rohde, A.M.; Rupp, J.; Tacconelli, E.; Vehreschild, M.J.G.T.; Walker, S.V.; Gastmeier, P.; Seifert, H.
Journal Article
2020Vasodilation of rat skeletal muscle arteries by the novel BK channel opener GoSlo is mediated by the simultaneous activation of BK and Kv7 channels
Zavaritskaya, O.; Dudem, S.; Ma, D.; Rabab, K.E.; Albrecht, S.; Tsvetkov, D.; Kassmann, M.; Thornbury, K.; Mladenov, M.; Kammermeier, C.; Sergeant, G.; Mullins, N.; Wouappi, O.; Wurm, H.; Kannt, A.; Gollasch, M.; Hollywood, M.A.; Schubert, R.
Journal Article
2020The venom gland transcriptome of the wasp spider Argiope bruennichi
Lüddecke, T.; Förster, F.; Billion, A.; Reumont, B.M. von; Vilcinskas, A.; Lemke, S.
Journal Article