Label-free detection of SARS-CoV-2 neutralizing antibodies in human serum by Bloch surface waves on 1D photonic crystal biochips

Occhicone, AgostinoAgostinoOcchiconeSinibaldi, AlbertoAlbertoSinibaldiPileri, TommasoTommasoPileriMatteo, Paola diPaola diMatteoChiappetta, DanieleDanieleChiappettaMunzert, PeterPeterMunzertDanz, NorbertNorbertDanzSonntag, FrankFrankSonntagAllegretti, M.M.AllegrettiPascale, V. deV. dePascaleMandoj, C.C.MandojConti, L.L.ContiMichelotti, F.F.Michelotti2023-07-042023-07-042022https://publica.fraunhofer.de/handle/publica/44510110.1364/FIO.2022.FTh1D.12-s2.0-85146767278We propose a rapid serologic test based on disposable nano-photonic biochips for SARS-CoV-2 related antibodies. The label-free sensograms showed that positive and negative human serum samples were discriminated, enabling real-time and fast label-free detection.enLabel-free detection of SARS-CoV-2 neutralizing antibodies in human serum by Bloch surface waves on 1D photonic crystal biochipsconference paper