Lohmann-Matthes, M.-L.Kiderlen, A.F.A.F.Kiderlen1986https://publica.fraunhofer.de/handle/publica/271624Resident and recruited macrophages (Mo) were extracted from various organs of the mouse (e. g. spleen, liver, peritoneal cavity). Early Mo-precursor cells and mature Mo were gained from bone marrow cultures. These Mo-populations are all spontaneously highly cytotoxic for promastigote Leihsmania as determind in a novel radiometric assay for Leishmania-lysis following effector-to-target association.demacrophage615610620doctoral thesis