Thiede, SebastianSebastianThiedeDér, AntalAntalDérMünnich, MarcMarcMünnichSobottka, ThomasThomasSobottka2024-07-092024-07-092024https://publica.fraunhofer.de/handle/publica/47116110.1007/978-3-031-34218-9_22-s2.0-85195457073The manufacturing industry is responsible for a large share of global environmental impacts (e.g., greenhouse gas emissions) that can mainly be tracked back to energy demand. This energy demand is determined by a diversity of processes and machines, which dynamically interact in process chains and with other factory elements such as technical building services (TBS). Given that, system-oriented material flow simulation with inclusion of energy aspects bears the potential to support the energy transition of industry through fostering both energy efficiency and substitution towards renewable resources. The chapter addresses the necessary background as well as common aspects in the context of energy-oriented manufacturing system simulation. Four manufacturing case studies underline the feasibility and potential of available simulation approaches for improving energy-related environmental impacts and also costs. Additionally, an outlook towards potential future research steps is given.enbook article