Gutwald, R.R.GutwaldJaeger, R.R.JaegerLambers, F.M.F.M.Lambers2022-03-052022-03-052017https://publica.fraunhofer.de/handle/publica/24953610.1080/10255842.2016.1240788The purpose of this paper was to analyze the biomechanical performance of customized mandibular reconstruction plates with optimized strength. The best locations for increasing bar widths were determined with a sensitivity analysis. Standard and customized plates were mounted on mandible models and mechanically tested. Maximum stress in the plate could be reduced from 573 to 393 MPa (-31%) by increasing bar widths. The median fatigue limit was significantly greater (p < 0.001) for customized plates (650 ± 27 N) than for standard plates (475 ± 27 N). Increasing bar widths at case-specific locations was an effective strategy for increasing plate fatigue performance.enmandibular reconstructionsensitivity analysisfinite element analysisfatigue testingimplant570journal article