Gelinsky, M.M.GelinskySpringer, A.A.SpringerHanke, T.T.HankeIwe, M.M.IweBastian, S.S.BastianIkonomidou, H.H.IkonomidouKühnel, D.D.KühnelBusch, W.W.BuschScholz, S.S.ScholzSchirmer, K.K.SchirmerMeissner, T.T.MeissnerRichter, V.V.RichterPotthoff, A.A.PotthoffPompe, W.W.Pompe2022-03-112022-03-112008https://publica.fraunhofer.de/handle/publica/3617362-s2.0-84869044288Engineered NP may be cytotoxic which was found not only to be due to the dissolution of toxic components, but might be a defined particle induced effect, not well understood until now. WC NP were found to be not toxic, whereas WC-Co NP were demonstrated to be highly cytotoxic for several cell types investigated in this study. Both are able to pass the outer cell membrane but can not get into the nuclei.enconference paper