Horsch, M.T.M.T.HorschChiacchiera, S.S.ChiacchieraLeite Cavalcanti, W.W.Leite CavalcantiSchembera, B.B.Schembera2022-03-062022-03-062021https://publica.fraunhofer.de/handle/publica/26790110.1007/978-3-030-68597-3_5This chapter addresses issues related to the practical use of the metadata standards, including syntactic interoperability and concrete scenarios from molecular modelling and simulation. It discusses challenges that arise from semantic heterogeneity, wherever multiple interoperability standards are concurrently employed for identical or overlapping domains of knowledge, or where domain ontologies need to be matched to top-level ontologies such as the European Materials and Modelling Ontology (EMMO).en620660671book article