Caggiano, A.A.CaggianoBruno, G.G.BrunoTeti, R.R.Teti2022-03-052022-03-052015https://publica.fraunhofer.de/handle/publica/24685610.1016/j.procir.2015.04.0222-s2.0-84939513801In this research paper, a novel approach to solve manufacturing scheduling problems based on the integration of optimisation and simulation tools is proposed. The advantages of this approach are illustrated with reference to a manufacturing scheduling case study. The initial optimisation model is formulated as an adaptation of the Capacitated Lot-Sizing Problem (CLSP). Then, a Discrete Event Simulation (DES) software is employed to verify the optimised solution and analyse its robustness taking into account uncertainties in the processing times and arrival rates, and a heuristic method is applied to improve the initial solution.enjournal article