Lankenau, A.A.LankenauRenner, A.A.RennerDuschl, C.C.Duschl2022-03-112022-03-112009https://publica.fraunhofer.de/handle/publica/36544410.1007/978-3-642-03887-7-50Local concentration patterns of certain compounds can direct the migration of animal cells and bacteria. This phenomenon is called chemotaxis. The analysis of chemotactic activity is a valuable diagnostic approach for the characterization of immune or tumour cells. Present assay formats are either time consuming or difficult to perform. We present a microfluidic device that allows fast and efficient analysis of the chemotactic activity of cells. Our approach is fully compatible with high-resolution optical microscopy and hence provides access to intracellular processes that may serve as early indicators of directed migration.en610conference paper