Tappe, D.D.TappeZidowitz, S.S.ZidowitzDemmer, P.P.DemmerKern, P.P.KernBarth, T.F.E.T.F.E.BarthFrosch, M.M.Frosch2022-03-042022-03-042010https://publica.fraunhofer.de/handle/publica/22134710.4269/ajtmh.2010.09-0462In this study we present, for the first time, a three-dimensional digital reconstruction of Echinococcus multilocularis larval growth in human tissue. Formalin-fixed, paraffin-embedded hepatic tissues from patients with alveolarechinococcosis were serially sectioned, stained, and areas of larval growth of the parasite were microphotographed. Parasitic structures were reconstructed from multiple digital planes, revealing a root-like network of interconnected vesiclesand tubules extending into the periphery of lesions.en616journal article