Bailer, SusanneSusanneBailerFunk, ChristinaChristinaFunk2024-04-242024-04-242022-02-09https://publica.fraunhofer.de/handle/publica/466817The present invention refers to a vector system, usable as a platform vector and suitable for the production of transgenic viruses of the subfamily Alphaherpesvirinae. Such transgenic viruses can be used as vaccine or as oncolytic virus or in gene therapy. The platform vector of the present invention is a vector system allowing a simplified search for and generation and production of viruses with a modified and increased functionality. The present invention refers also to the use of the platform vector as a vector system for the generation and the production of transgenic viruses, methods for the production of a transgenic virus, using the vector system of the present invention and viruses obtained by such methods.enpatentEP3950948 A1EP20200190134