Kretov, EgorEgorKretovScheel, Jan-PhilippJan-PhilippScheelMirzojan, LianaLianaMirzojanSevecke, FlorianFlorianSeveckeGräser, MatthiasMatthiasGräser2024-05-032024-05-032024https://publica.fraunhofer.de/handle/publica/46714710.18416/ijmpi.2024.24030022-s2.0-85187478190The implementation of human-scale magnetic particle imaging is significantly restricted by the nonlinear growth in power with the size of the field-generating coils. To address this issue, we developed anatomically optimized shapes with a reduced internal volume for the head drive field system using a wide range of anatomical data as a reference. On the base of designed complex bodies, we synthesized windings for two orthogonal coils with the help of the stream functions approach. The resulting coil set was compared to the state-of-the-art solenoid/saddle coil pair and showed a reduction in power consumption by a factor of 1.58 in numerical simulations. We also built a prototype of the designed coils using additive manufacturing and used it to receive the first signals from the nanoparticles.enPower-optimized drive field coils for human brain magnetic particle imagingjournal article