Dincer, C.C.DincerKtaich, R.R.KtaichLaubender, E.E.LaubenderHees, J.J.J.J.HeesKieninger, J.J.KieningerNebel, C.E.C.E.NebelHeinze, J.J.HeinzeUrban, G.A.G.A.Urban2022-03-052022-03-052015https://publica.fraunhofer.de/handle/publica/24633410.1016/j.electacta.2015.10.113In this paper we present nanocrystalline boron-doped diamond nanoelectrode arrays (BDD-NEAs) for the low-level detection of biogenic substances such as dopamine (DA) without the need for a selective membrane. We achieved a sensitive and reproducible detection of dopamine in the presence of ascorbic acid (AA) with oxygen (O-) terminated BDD-NEAs. To improve the peak separation between dopamine and ascorbic acid, differential pulse voltammetry (DPV) was employed. Therewith, it was possible to measure dopamine with a sensitivity of 57.9 nA mM−1 cm−2. The detection limit was less than 100 nM with a linear behavior up to a concentration of 20 mM. The choice of the appropriate termination, the combination of the advantages of nanoelectrode arrays together with the outstanding electrochemical properties of boron-doped diamond and the right measurement method allowed successful measurement of dopamine in physiological concentrations in the presence of ascorbic acid.en541journal article